Journal

Biochemistry

ISSN 0006-2960 · American Chemical Society

Published here

252 counted works of 256 linked

YearTitleAcademicsSources
2026 Back to the Future of Biochemistry: Recent Advances from Past Contributors Jeremy M. Baskin GS
2026 Comparative simulations of conformational flexibility during radical transport in ribonucleotide reductase Sharon Hammes-Schiffer CV
2025 A balancing act: Thymine DNA glycosylase combines sequence and rotational preferences to define lesion excision in the nucleosome core particle Sarah Delaney CV OA
2025 The ERVK3-1 microprotein interacts with the HUSH complex Sarah Slavoff GS
2024 A conserved C-terminal tail is responsible for membrane localization and function of Pseudomonas aeruginosa hemerythrin related record Michael J. Ragusa GS
2024 Conserved C-Terminal Tail Is Responsible for Membrane Localization and Function of Pseudomonas aeruginosa Hemerythrin Michael J. Ragusa GS
2024 Proton-coupled electron transfer upon oxidation of tyrosine in a de novo protein: Analysis of proton acceptor candidates Sharon Hammes-Schiffer CV
2023 A comparative analysis of the membrane binding and remodeling properties of two related sorting nexin complexes involved in autophagy Michael J. Ragusa GS
2023 Chemoproteomic profiling of 8-oxoguanosine-sensitive RNA-protein interactions Ralph Kleiner CV OA
2023 Local Xenon–Protein Interaction Produces Global Conformational Change and Allosteric Inhibition in Lysozyme Ivan J. Dmochowski OA GS
2022 Kinetic Analysis of the Effect of N-terminal Acetylation in Thymine DNA Glycosylase Sarah Delaney CV OA
2022 Peptide-Dependent Growth in Yeast Via Fine-Tuned Peptide/GPCR-Activated Gene Expression in progress Virginia W. Cornish CV OA
2021 Design of a Superpositively Charged Enzyme: Human Carbonic Anhydrase II Variant with Ferritin Encapsulation and Immobilization Ivan J. Dmochowski OA GS
2021 Genetic Code Expansion: A Brief History and Perspective Virginia W. Cornish CV OA
2021 Nucleosome core particles lacking H2B or H3 tails are altered structurally and have differential base excision repair fingerprints Sarah Delaney CV OA
2020 Cytoskeletal drugs modulate off-target protein folding landscapes inside cells Caitlin Davis GS
2020 Dimeric stilbene antibiotics target the bacterial cell wall in drug-resistant gram-positive pathogens Jason M. Crawford GS
2020 Examining the mechanism of phosphite dehydrogenase with quantum mechanical/molecular mechanical free energy simulations Sharon Hammes-Schiffer CV
2020 Global profiling of cellular substrates of human Dcp2 Sarah Slavoff GS
2020 Quantifying the Relationship between Conformational Dynamics and Enzymatic Activity in Ribonuclease HI Homologues Paul Robustelli CV OA
2020 The Heme-Lys Cross-link in Cytochrome P460 Promotes Catalysis by Enforcing Secondary Coordination Sphere Architecture Kyle M. Lancaster CV OA GS
2020 The NBDY microprotein regulates cellular RNA decapping Sarah Slavoff GS
2019 Characterization of a Hybrid Nonribosomal Peptide–Carbohydrate Biosynthetic Pathway in Photorhabdus luminescens Jason M. Crawford GS
2019 Interrogation of Eukaryotic Stop Codon Readthrough Signals by In Vitro RNA Selection Virginia W. Cornish CV OA
2019 In vitro selection with a site-specifically modified RNA library reveals the binding preferences of N6-methyladenosine (m6A) reader proteins Ralph Kleiner CV OA
2019 Stuffed methyltransferase catalyzes the penultimate step of pyochelin biosynthesis Squire J. Booker GS
2019 Taking a STAP at Core Promoter–Transcriptional Cofactor Specificity Brian Liau GS
2019 The complex between a multi-junction DNA motif, PX-DNA, and T7 endonuclease I Megan Kizer CV OA GS
2018 A quantitative model for BicD2/cargo interactions Megan Kizer CV OA GS
2018 A Yeast Three Hybrid Assay for Metabolic Engineering of Tetracycline Derivatives Virginia W. Cornish CV OA
2018 Characterization of 1,2-propanediol dehydratases reveals distinct mechanisms for B12-dependent and glycyl radical enzymes. Emily Balskus CV OA
2018 Characterization of Natural Colibactin–Nucleobase Adducts by Tandem Mass Spectrometry and Isotopic Labeling. Support for DNA Alkylation by Cyclopropane Ring Opening Jason M. Crawford GS
2018 Comparative membrane proteomics reveals a nonannotated E. coli heat shock protein Sarah Slavoff GS
2018 D-Amino Acid Mediated Translation Arrest Is Modulated by the Identity of the Incoming Aminoacyl-tRNA Virginia W. Cornish; Ruben L Gonzalez Jr CV OA GS
2018 Deciphering human gut microbiota-nutrient interactions: A role for biochemistry. Emily Balskus CV OA
2018 DNA repair: Unconventional lesions require unconventional repair Seth Herzon CV OA
2018 Enhanced Solubilization of Class B Radical S‑Adenosylmethionine Methylases by Improved Cobalamin Uptake in Escherichia coli Squire J. Booker GS
2018 Ex uno plura: differential labeling of phospholipid biosynthetic pathways with a single bioorthogonal alcohol Jeremy M. Baskin GS
2018 Functional Characterization of a Condensation Domain That Links Nonribosomal Peptide and Pteridine Biosynthetic Machineries in Photorhabdus luminescens Jason M. Crawford GS
2018 Gut microbiota: Rational manipulation of gut bacterial metalloenzymes provides insights into dysbiosis and inflammation. Emily Balskus CV OA
2018 Human oxoguanine glycosylase 1 removes solution accessible 8-oxo-7,8-dihydroguanine lesions from globally substituted nucleosomes except in the dyad region Sarah Delaney CV OA
2018 Labeling for Quantitative Comparison of Imaging Measurements in Vitro and in Cells Caitlin Davis GS
2018 Mapping the small molecule interactome by mass spectrometry Christina Woo CV OA
2018 Microbiota-regulated outcomes of human cancer immunotherapy via the PD-1/PD-L1 axis Jason M. Crawford GS
2018 Optochemical control of protein localization and activity within cell-like compartments David M. Chenoweth GS
2018 P-bodies: composition, properties, and functions Sarah Slavoff GS
2018 Reading the RNA Code Ralph Kleiner CV OA
2018 So Close, Yet Sulfur Away: Opening the Nitrogenase Cofactor Structure Creates a Binding Site Patrick Holland CV OA GS
2018 Stereochemical and Mechanistic Investigation of the Reaction Catalyzed by Fom3 from Streptomyces fradiae, a Cobalamin-Dependent Radical S‑Adenosylmethionine Methylase Squire J. Booker GS
2018 The Eponymous Cofactors in Cytochrome P460s from Ammonia- Oxidizing Bacteria Are Iron Porphyrinoids Whose Macrocycles Are Dibasic Kyle M. Lancaster CV OA GS
2017 A new nucleoside antibiotic chokes bacterial RNA polymerase Jason M. Crawford GS
2017 Fluorescence Polarization Assay for Small Molecule Screening of FK506 Biosynthesized in 96-Well Microtitre Plates Virginia W. Cornish CV OA
2017 Identification of a Small Molecule Activator for AphB, a LysR-Type Virulence Transcriptional Regulator in Vibrio cholerae in progress F. Jon Kull CV OA
2017 Mechanistic Insight from Calorimetric Measurements of the Assembly of the Binuclear Metal Active Site of Glycerophosphodiesterase (GpdQ) from Enterobacter aerogenes Dean E. Wilcox OA GS
2017 Site-Specific Fluorescence Polarization for Studying the Disaggregation of α‑Synuclein Fibrils by Small Molecules E. James Petersson; Tobias Baumgart GS
2017 Specificity and Speed: Tethered Photopharmacology Dirk Trauner CV OA GS
2017 Thermophilic Ferritin 24mer Assembly and Nanoparticle Encapsulation Modulated by Interdimer Electrostatic Repulsion Ivan J. Dmochowski OA GS
2016 Characterization of a Copper-binding Mutant of the Organomercurial Lyase MerB: Insight into Metal Binding Specificity and Redirected Protein Function Dean E. Wilcox CV
2016 Characterization of Lipoyl Synthase from Mycobacterium tuberculosis Squire J. Booker GS
2016 Molecular dynamics study of twister ribozyme: Role of Mg2+ ions and the hydrogen-bonding network in the active site Sharon Hammes-Schiffer CV
2016 Structural and Biochemical Characterization of a Copper-Binding Mutant of the Organomercurial Lyase MerB: Insight into the Key Role of the Active Site Aspartic Acid in Hg–Carbon Bond Cleavage and Metal Binding Specificity Dean E. Wilcox OA GS
2016 Transformations of the FeS clusters of the methylthiotransferases MiaB and RimO, detected by direct electrochemistry Squire J. Booker GS
2015 Efficient Delivery of Long-Chain Fatty Aldehydes from the Nostoc punctiforme Acyl–Acyl Carrier Protein Reductase to Its Cognate Aldehyde-Deformylating Oxygenase Squire J. Booker GS
2015 Fast helix formation in the B domain of protein A revealed by site-specific infrared probes Caitlin Davis GS
2015 Inverse thio effects in the hepatitis delta virus ribozyme reveal that the reaction pathway is controlled by metal ion charge density Sharon Hammes-Schiffer CV GS
2015 Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion Between the all-trans and 13-cis Retinal Isomers Dirk Trauner CV OA GS
2015 Moving protons and electrons in biomimetic systems James Mayer GS
2015 Structure-based small molecule modulation of a pre-amyloid state: pharmacological enhancement of iapp membrane-binding and toxicity Elizabeth Rhoades GS
2014 BIN1 membrane curvature sensing and generation show autoinhibition regulated by downstream ligands and PI (4, 5) P2 Tobias Baumgart GS
2014 Characterization of the lipid binding properties of Otoferlin reveals specific interactions between PI (4, 5) P2 and the C2C and C2F domains E. James Petersson GS
2014 Evidence for a catalytically and kinetically competent enzyme–substrate cross-linked intermediate in catalysis by lipoyl synthase Squire J. Booker GS
2014 Experimental and computational mutagenesis to investigate the positioning of a general base within an enzyme active site Sharon Hammes-Schiffer CV
2014 Protein engineering of the N-terminus of NEMO: structure stabilization and rescue of IKKβ binding Dale F. Mierke GS
2014 Thermodynamic Contributions to the Stability of the Insulin Hexamer Dean E. Wilcox CV OA GS
2014 Thermodynamics of Formation of the Insulin Hexamer: Metal-Stabilized Proton-Coupled Assembly of Quaternary Structure Dean E. Wilcox CV OA GS
2014 WW domain folding complexity revealed by infrared spectroscopy Caitlin Davis GS
2013 A Photoswitchable Neurotransmitter Analogue Bound to its Receptor Dirk Trauner CV OA GS
2013 A Population-Based Experimental Model for Protein Evolution: Effects of Mutation Rate and Selection Stringency on Evolutionary Outcomes David R. Liu CV
2013 Catalytic efficiency of enzymes: A theoretical analysis Sharon Hammes-Schiffer CV GS
2013 Further characterization of Cys-type and Ser-type anaerobic sulfatase maturating enzymes suggests a commonality in mechanism of catalysis Squire J. Booker GS
2013 Identification of the catalytic Mg2+ ion in the hepatitis delta virus ribozyme Sharon Hammes-Schiffer CV GS
2013 Mutation of lysine 317 in the D2 subunit of photosystem II alters chloride binding and proton transport Gary Brudvig GS
2013 S0‑State Model of the Oxygen-Evolving Complex of Photosystem II Gary Brudvig GS
2013 Single-molecule dynamics and mechanisms of metalloregulators and metallochaperones Peng Chen GS
2013 Thio effects and an unconventional metal ion rescue in the genomic hepatitis delta virus ribozyme Sharon Hammes-Schiffer CV GS
2013 Transient-state kinetics of apurinic/apyrimidinic (AP) endonuclease 1 acting on an authentic AP site and commonly-used substrate analogs: The effect of diverse metal ions and base mismatches Sarah Delaney CV OA
2013 α-Synuclein can inhibit SNARE-mediated vesicle fusion through direct interactions with lipid bilayers Elizabeth Rhoades GS
2012 A DNA-Based Nanomechanical Device Used To Characterize the Distortion of DNA by Apo-SoxR Protein Eunsuk Kim CV OA GS
2012 CAG/CTG repeats alter affinity for the histone core and positioning of DNA in the nucleosome Sarah Delaney CV OA
2012 Conformational Change in Rhomboid Protease GlpG Induced by Inhibitor Binding to Its S′ Subsites Jon Ellman CV OA GS
2012 Evidence for only oxygenative cleavage of aldehydes to alk (a/e) nes and formate by cyanobacterial aldehyde decarbonylases Squire J. Booker GS
2012 Schiff base protonation changes in siberian hamster ultraviolet cone pigment photointermediates E. Chui-Ying Yan CV OA
2012 Trinucleotide repeat DNA alters structure to minimize the thermodynamic impact of 8-oxo-7,8-dihydroguanine Sarah Delaney CV OA
2011 Biosynthetic chlorination of the piperazate residue in kutzneride biosynthesis by KthP Frank C. Schroeder GS
2011 Flexibility, diversity, and cooperativity: Pillars of enzyme catalysis Sharon Hammes-Schiffer CV GS
2011 Functional model of metabolite gating by human voltage-dependent anion channel 2 Ann E. McDermott GS
2011 Metal binding motif in the active site of the HDV ribozyme binds divalent and monovalent ions Sharon Hammes-Schiffer CV GS
2011 Molecular Investigations of the Structure and Function of the Protein Phosphatase 1: Spinophilin: Inhibitor-2 Heterotrimeric Complex Michael J. Ragusa GS
2011 Mutations that replace aromatic side chains promote aggregation of the Alzheimer’s Ab peptide Michael Hecht CV OA
2011 S1-State Model of the O2-Evolving Complex of Photosystem II Gary Brudvig GS
2011 Structural/functional role of chloride in photosystem II Gary Brudvig GS
2011 Structure of even/odd trinucleotide repeat sequences modulates persistence of non-B conformations and conversion to duplex Sarah Delaney CV OA
2011 Water in the active site of ketosteroid isomerase Sharon Hammes-Schiffer CV
2010 A Basic Sequence in STIM1 Promotes Ca2+ Influx by Interacting with the C-Terminal Acidic Coiled Coil of Orai1 Barbara A. Baird CV OA GS
2010 A consensus mechanism for radical SAM-dependent dehydrogenation? BtrN contains two [4Fe–4S] clusters Squire J. Booker GS
2010 AGG Interruptions in (CGG)n DNA repeat tracts modulate the structure and thermodynamics of non-B conformations in vitro Sarah Delaney CV OA
2010 Dihydropyrimidinone positive modulation of δ-subunit-containing γ-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant Bruce Ganem GS
2010 Hydrogen bonding in the active site of ketosteroid isomerase: Electronic inductive effects and hydrogen bond coupling Sharon Hammes-Schiffer CV GS
2010 Hydrophobic residues in helix 8 of cannabinoid receptor 1 are critical for structural and functional properties Dale F. Mierke GS
2010 Quantitative Characterization of the Interactions among c-myc Transcriptional Regulators FUSE, FBP, and FIR Elizabeth Rhoades GS
2010 Structure of epi-isozizaene synthase from Streptomyces coelicolor A3 (2), a platform for new terpenoid cyclization templates David W. Christianson GS
2010 Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological function David W. Christianson GS
2009 Characterization of RimO, a new member of the methylthiotransferase subclass of the radical SAM superfamily Squire J. Booker GS
2009 Crystal structure of (+)-δ-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysis David W. Christianson GS
2009 GRK2 activation by receptors: role of the kinase large lobe and carboxyl terminal tail Michael J. Ragusa GS
2009 Hybrid quantum/classical molecular dynamics simulations of the proton transfer reactions catalyzed by ketosteroid isomerase: Analysis of hydrogen bonding, conformational motions, and electrostatics Sharon Hammes-Schiffer CV GS
2009 IgE Receptor-Mediated Alteration of Membrane-Cytoskeleton Interactions Revealed by Mass Spectrometric Analysis of Detergent-Resistant Membranes Barbara A. Baird CV OA GS
2009 Morphology and secondary structure of stable β-oligomers formed by amyloid peptide PrP (106− 126) Patrick J. Walsh GS
2009 Structure-dependent DNA damage and repair in a trinucleotide repeat sequence Sarah Delaney CV OA
2009 Substrate-triggered formation and remarkable stability of the C–H bond-cleaving chloroferryl intermediate in the aliphatic halogenase, SyrB2. Megan L. Matthews CV OA GS
2009 α-Synuclein Binds Large Unilamellar Vesicles as an Extended Helix† Elizabeth Rhoades GS
2008 Binding Mechanisms of PEGylated Ligands Reveal Multiple Effects of the PEG Scaffold Barbara A. Baird CV OA GS
2008 Characterization of quinolinate synthases from Escherichia coli, Mycobacterium tuberculosis, and Pyrococcus horikoshii indicates that [4Fe-4S] clusters are common cofactors … Squire J. Booker GS
2008 Directing noble metal ion chemistry within a designed ferritin protein Ivan J. Dmochowski; David W. Christianson CV OA GS
2008 Free energy landscape of enzyme catalysis Sharon Hammes-Schiffer CV GS
2008 In vitro characterization of AtsB, a radical SAM formylglycine-generating enzyme that contains three [4Fe-4S] clusters Squire J. Booker GS
2008 Mapping peptide hormone–receptor interactions using a disulfide-trapping approach Dale F. Mierke GS
2008 Regulation of the activity of Escherichia coli quinolinate synthase by reversible disulfide-bond formation Squire J. Booker GS
2008 Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors, David W. Christianson GS
2007 AurF from Streptomyces thioluteus and a possible new family of manganese/iron oxygenases. Megan L. Matthews CV OA GS
2007 Thermodynamics of Ni2+, Cu2+, and Zn2+ Binding to the Urease Metallochaperone UreE Dean E. Wilcox OA GS
2007 The substrate specificity of MutY for hyperoxidized guanine lesions in vivo Sarah Delaney CV OA
2007 X-ray crystal structure of aristolochene synthase from Aspergillus terreus and the evolution of templates for the cyclization of farnesyl diphosphate David W. Christianson GS
2006 Engineering Light-Gated Ion Channels Dirk Trauner CV OA GS
2006 Solution Structure and Folding Characteristics of the C-terminal SH3 Domain of c-Crk-II. Tom Muir CV OA GS
2006 The mid-region of parathyroid hormone (1− 34) serves as a functional docking domain in receptor activation Dale F. Mierke GS
2005 Association of the cystic fibrosis transmembrane regulator with CAL: structural features and molecular dynamics Dale F. Mierke GS
2004 Correlation Between Catalytic Efficiency and the Transcription Read-Out in Chemical Complementation, a High-Throughput Assay for Enzyme Catalysis Virginia W. Cornish CV OA
2004 Correlation Between Ligand-Receptor Affinity and the Transcription Readout in a Yeast Three-Hybrid System Virginia W. Cornish CV OA
2004 Escherichia coli Lipoyl Synthase Binds Two Distinct [4Fe−4S] Clusters per Polypeptide Squire J. Booker GS
2004 Insight into the polar reactivity of the onium chalcogen analogues of S-adenosyl-L-methionine Squire J. Booker GS
2004 Isotope and elemental effects indicate a rate-limiting methyl transfer as the initial step in the reaction catalyzed by Escherichia coli cyclopropane fatty acid synthase Squire J. Booker GS
2004 Lipoyl synthase requires two equivalents of S-adenosyl-L-methionine to synthesize one equivalent of lipoic acid Squire J. Booker GS
2004 Oxygen activation by the noncoupled binuclear copper site in peptidylglycine α-hydroxylating monooxygenase. Spectroscopic definition of the resting sites and the putative CuIIM … Peng Chen GS
2004 Redox functions of carotenoids in photosynthesis Gary Brudvig GS
2004 Resonance Raman Analysis of the Mechanism of Energy Storage and Chromophore Distortion in the Primary Visual Photoproduct E. Chui-Ying Yan CV OA
2004 Semisynthesis of Phosphovariants of SMAD2 Reveals a Substrate Preference of the Activated TR1 Kinase. Tom Muir CV OA GS
2004 Structure of Human Epoxide Hydrolase Reveals Mechanistic Inferences on Bifunctional Catalysis in Epoxide and Phosphate Ester Hydrolysis, David W. Christianson GS
2004 Toward parathyroid hormone minimization: Conformational studies of cyclic PTH (1− 14) analogues Dale F. Mierke GS
2003 Active site loop motion in triosephosphate isomerase: T-jump relaxation spectroscopy of thermal activation Ann E. McDermott GS
2003 Charge transport in DNA duplex/quadruplex conjugates Sarah Delaney CV OA
2003 Highly Effective Poly(Ethylene Glycol) Architectures for Specific Inhibition of Immune Receptor Activation Barbara A. Baird CV OA GS
2003 Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal, David W. Christianson GS
2003 Ionic states of substrates and transition state analogues at the catalytic sites of N-ribosyltransferases Ann E. McDermott GS
2002 Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttle David W. Christianson GS
2002 Function of Extracellular Loop 2 in Bovine Rhodopsin: Glutamic Acid 181 Modulates Stability and Wavelength Maximal Absorption of Metarhodopsin II E. Chui-Ying Yan CV OA
2002 Identification of the principal binding site for RGD-containing ligands in the αvβ3 integrin: a photoaffinity cross-linking study Dale F. Mierke GS
2002 Impact of enzyme motion on activity Sharon Hammes-Schiffer CV GS
2002 Intermolecular Interactions between Cholecystokinin-8 and the Third Extracellular Loop of the Cholecystokinin-2 Receptor, Dale F. Mierke GS
2002 Key determinants of receptor activation in the agr autoinducing peptides of Staphylococcus aureus Tom Muir CV OA GS
2002 Structure of the third intracellular loop of the human cannabinoid 1 receptor Dale F. Mierke GS
2002 The Novel Binding Mode of N-Alkyl-N‘-hydroxyguanidine to Neuronal Nitric Oxide Synthase Provides Mechanistic Insights into NO Biosynthesis Ming Xian GS
2002 X-ray Crystal Structures of D100E Trichodiene Synthase and Its Pyrophosphate Complex Reveal the Basis for Terpene Product Diversity, David W. Christianson GS
2001 Characterization of carotenoid and chlorophyll photooxidation in photosystem II Gary Brudvig GS
2001 Fluorescence Anisotropy Measurements of Lipid Order in Plasma Membranes and Lipid Rafts from RBL-2H3 Mast Cells Barbara A. Baird CV OA GS
2001 Mechanistic and Metabolic Inferences from the Binding of Substrate Analogues and Products to Arginase, David W. Christianson GS
2001 Photoaffinity labeling of mutant neurokinin-1 receptors reveals additional structural features of the substance P/NK-1 receptor complex Dale F. Mierke GS
2001 Probing Erectile Function: S-(2-Boronoethyl)-l-Cysteine Binds to Arginase as a Transition State Analogue and Enhances Smooth Muscle Relaxation in Human Penile … David W. Christianson GS
2001 Quantifying the Ion Selectivity of the Ca2+ Site in Photosystem II: Evidence for Direct Involvement of Ca2+ in O2 Formation Gary Brudvig GS
2000 Characterization of parathyroid hormone/receptor interactions: structure of the first extracellular loop Dale F. Mierke GS
2000 Cooperative Thermal Denaturation of Proteins Designed by Binary Patterning of Polar and Nonpolar Amino Acids Michael Hecht CV OA
2000 Direct FeS cluster involvement in generation of a radical in lysine 2, 3-aminomutase Squire J. Booker GS
2000 Heterogeneous Glycosylation of Immunoglobulin E Constructs Characterized by Top-Down High-Resolution 2-D Mass Spectrometry Barbara A. Baird CV OA GS
2000 Lysine 2, 3-aminomutase and trans-4, 5-dehydrolysine: characterization of an allylic analogue of a substrate-based radical in the catalytic mechanism Squire J. Booker GS
2000 Mapping the Bimolecular Interface of the Parathyroid Hormone (PTH)−PTH1 Receptor Complex: Spatial Proximity between Lys27 (of the Hormone Principal Binding Domain … Dale F. Mierke GS
2000 Probing the Catalytic Mechanism of Prephenate Dehydratase by Site-Directed Mutagenesis of the Escherichia coli P-Protein Dehydratase Domain Bruce Ganem GS
1999 Deuterium magic angle spinning studies of substrates bound to cytochrome P450 Ann E. McDermott GS
1999 H-Bonding Maintains the Active Site of Type I Copper Proteins: Site-Directed Mutagenesis of Asn38 in Poplar Plastocyanin Michael Hecht CV OA
1999 Interleukin 1 (IL-1) Causes Changes in Lateral and Rotational Mobilities of IL-1 Type I Receptors Barbara A. Baird CV OA GS
1999 Molecular characterization of the receptor− ligand complex for parathyroid hormone Dale F. Mierke GS
1999 Molecular complex of cholecystokinin-8 and N-terminus of the cholecystokinin A receptor by NMR spectroscopy Dale F. Mierke GS
1999 Quantitative Analysis of Phospholipids in Functionally Important Membrane Domains from RBL-2H3 Mast Cells Using Tandem High-Resolution Mass Spectrometry Barbara A. Baird CV OA GS
1999 Regulation of Phenylalanine Biosynthesis. Studies on the Mechanism of Phenylalanine Binding and Feedback Inhibition in the Escherichia coli P-Protein Bruce Ganem GS
1999 Solid state NMR studies of hydrogen bonding in a citrate synthase inhibitor complex Ann E. McDermott GS
1999 Studies on the catalysis of carbon− cobalt bond homolysis by ribonucleoside triphosphate reductase: Evidence for concerted carbon− cobalt bond homolysis and thiyl radical formation Squire J. Booker GS
1998 Binding Domain of Human Parathyroid Hormone Receptor: From Conformation to Function, Dale F. Mierke GS
1998 S-Adenosylmethionine-Dependent Reduction of Lysine 2,3-Aminomutase and Observation of the Catalytically Functional Iron−Sulfur Centers by Electron … Squire J. Booker GS
1998 Studying Receptor-Ligand Interactions Using Encoded Amino Acid Scanning Tom Muir CV
1997 Altered Patterns of Tyrosine Phosphorylation and Syk Activation for Sterically Restricted Cyclic Dimers of IgE-FcRI Barbara A. Baird CV OA GS
1997 Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function David W. Christianson GS
1997 An Experimental Approach to Evaluating the Role of Backbone Interactions in Proteins Using Unnatural Amino Acid Mutagenesis Virginia W. Cornish CV OA
1997 Conformational Studies of Mono- and Bicyclic Parathyroid Hormone-Related Protein-Derived Agonists† Dale F. Mierke GS
1997 Evidence Supporting a Role for Microfilaments in Regulating the Coupling between Poorly Dissociable IgE-FcRI Aggregates and Downstream Signaling Pathways Barbara A. Baird CV OA GS
1997 Histidine→ carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activity David W. Christianson GS
1997 Molecular Dynamics of the Unfolding of Barnase in Water and 8M Aqueous Urea William Jorgensen CV OA GS
1997 Mono-and bicyclic analogs of parathyroid hormone-related protein. 2. Conformational analysis of antagonists by CD, NMR, and distance geometry calculations Dale F. Mierke GS
1997 Studying Receptor Ligand Interactions Using Encoded Amino Acid Scanning related record Tom Muir CV OA
1997 Synthesis, Stereochemistry, and Biological Activity of 1α,23,25-Trihydroxy-24-oxovitamin D3, a Major Natural Metabolite of 1α,25-Dihydroxyvitamin D3 Paul Williard CV OA GS
1996 Expression in yeast and purification of functional macrophage nitric oxide synthase. Evidence for cysteine-194 as iron proximal ligand Squire J. Booker GS
1996 Identification of two functionally different classes of exocellulases Bruce Ganem GS
1996 Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase II David W. Christianson GS
1996 The Fc Segment of IgE Influences the Kinetics of Dissociation of a Symmetrical Bivalent Ligand from Cyclic Dimeric Complexes Barbara A. Baird CV OA GS
1995 Alteration of Lipid Composition Modulates FcRI Signaling in RBL-2H3 Cells Barbara A. Baird CV OA GS
1995 Dynamics of the flexible loop of triose-phosphate isomerase: the loop motion is not ligand gated Ann E. McDermott GS
1995 Effects of Subunit Mutation on the Rotational Dynamics of FcRI, the High Affinity Receptor for IgE, in Transfected cells Barbara A. Baird CV OA
1995 Is burst hydrophobic collapse necessary for protein folding? Eugene I. Shakhnovich GS
1994 Coenzyme B12-dependent ribonucleotide reductase: evidence for the participation of five cysteine residues in ribonucleotide reduction Squire J. Booker GS
1994 Design and Chemical Synthesis of a Neo-Protein Structural Model for the Cytoplasmic Domain of a Multi-Subunit Cell-Surface Receptor: Integrin IIb3 (Platelet GP11b-IIIa). Tom Muir CV OA GS
1994 Determination of internuclear distances and the orientation of functional groups by solid-state NMR: rotational resonance study of the conformation of retinal in bacteriorhodopsin Ann E. McDermott GS
1994 Deuterium solid-state nuclear magnetic resonance studies of methyl group dynamics in bacteriorhodopsin and retinal model compounds: evidence for a 6-s-trans chromophore in the … Ann E. McDermott GS
1994 Specific nucleus as the transition state for protein folding: evidence from the lattice model Eugene I. Shakhnovich GS
1994 Stabilizing and Destabilizing Effects of Placing b-Branched Amino Acids in Protein a-Helices Virginia W. Cornish CV OA
1993 Determination of Fe-CO geometry in the subunits of carbonmonoxy hemoglobin M Boston using femtosecond IR spectroscopy Tianquan “Tim” Lian CV OA
1993 Mechanism for the Rotamase Activity of FK506 Binding Protein from Molecular Dynamics Simulations. William Jorgensen CV OA
1993 Molecular Dynamics Simulations of the Unfolding of Apomyoglobin in Water. William Jorgensen CV OA GS
1993 New evidence for a membrane-bound pathway in hormone receptor binding Dale F. Mierke GS
1993 Spectroscopic evidence from site-directed mutants of Synechocystis PCC6803 in favor of a close interaction between histidine 189 and redox-active tyrosine 160, both of … Gary Brudvig GS
1992 Aggregation of IgE- Receptor Complexes on Rat Basophilic Leukemia Cells Does Not Change the Intrinsic Affinity but Can Alter the Kinetics of the Ligand-IgE Interaction Barbara A. Baird CV OA GS
1992 A model for the role of multiple cysteine residues involved in ribonucleotide reduction: amazing and still confusing Squire J. Booker GS
1992 Dynamic Conformations Compared for IgE and IgG1 in Solution and Bound to Receptors Barbara A. Baird CV OA GS
1992 Photooxidation of cytochrome b559 in oxygen-evolving photosystem II Gary Brudvig GS
1992 Rotational Motion of Monomeric and Dimeric Immunoglobulin E-Receptor Complexes Barbara A. Baird CV OA GS
1992 Rotational resonance NMR study of the active site structure in bacteriorhodopsin: conformation of the Schiff base linkage Ann E. McDermott GS
1991 An unusual peptide conformation may precipitate amyloid formation in Alzheimer's disease: application of solid-state NMR to the determination of protein secondary structure Ann E. McDermott GS
1991 Bivalent Ligand Dissociation Kinetics from Receptor-Bound Immunoglobulin E: Evidence for a Time-Dependent Increase in Ligand Rebinding at the Cell Surface Barbara A. Baird CV OA GS
1991 Conformational mobility of His-64 in the Thr-200. fwdarw. Ser mutant of human carbonic anhydrase II David W. Christianson GS
1991 Conformations of IgE Bound to Its Receptor FcRI and in Solution Barbara A. Baird CV OA GS
1991 Dissociation Kinetics of Bivalent Ligand- Immunoglobulin E Aggregates in Solution Barbara A. Baird CV OA GS
1991 Engineering the hydrophobic pocket of carbonic anhydrase II David W. Christianson GS
1991 Mechanism of proton pumping in bacteriorhodopsin by solid-state NMR: the protonation state of tyrosine in the light-adapted and M states Ann E. McDermott GS
1991 Molecular Dynamics Simulations of the Unfolding of an -Helical Analog of Ribonuclease-A S-Peptide in Water. William Jorgensen CV OA GS
1991 Nitrogen ligation to manganese in the photosynthetic oxygen-evolving complex: continuous-wave and pulsed EPR studies of photosystem II particles containing nitrogen-14 or … Ann E. McDermott GS
1990 A Nanosecond Fluorescence Depolarization Study on the Segmental Flexibility of Receptor-Bound Immunoglobulin E Barbara A. Baird CV OA GS
1990 Conformational studies by circular dichroism, proton NMR, and computer simulations of bombolitins I and III in aqueous solution containing surfactant micelles Dale F. Mierke GS
1990 Conformations of bombolitins I and III aqueous solutions: circular dichroism, proton NMR, and computer simulation studies Dale F. Mierke GS
1990 Electron-transfer reactions in manganese-depleted photosystem II Gary Brudvig GS
1990 Rotational resonance determination of the structure of an enzyme-inhibitor complex: phosphorylation of an (aminoalkyl) phosphinate inhibitor of D-alanyl-D-alanine ligase by ATP Ann E. McDermott GS
1990 Solid-state carbon-13 NMR study of tyrosine protonation in dark-adapted bacteriorhodopsin Ann E. McDermott GS
1990 The S0 state of photosystem II induced by hydroxylamine: differences between the structure of the manganese complex in the S0 and S1 states determined by X-ray absorption … Ann E. McDermott GS
1990 The S3 state of photosystem II: differences between the structure of the manganese complex in the S2 and S3 states determined by X-ray absorption spectroscopy Ann E. McDermott GS
1989 Directed alteration of the D1 polypeptide of photosystem II: evidence that tyrosine-161 is the redox component, Z, connecting the oxygen-evolving complex to the primary … Gary Brudvig GS
1989 EXAFS structural study of FX, the low-potential iron-sulfur center in photosystem I Ann E. McDermott GS
1989 Manganese and calcium requirements for reconstitution of oxygen-evolution activity in manganese-depleted photosystem II membranes Gary Brudvig GS
1989 Molecular basis of the heat denaturation of photosystem II Gary Brudvig GS
1988 Characterization of the manganese oxygen-evolving complex and the iron-quinone acceptor complex in photosystem II from a thermophilic cyanobacterium by electron paramagnetic … Ann E. McDermott GS
1988 Cytochrome b-559 may function to protect photosystem II from photoinhibition Gary Brudvig GS
1987 Comparison of the structure of the manganese complex in the S1 and S2 states of the photosynthetic oxygen-evolving complex: an x-ray absorption spectroscopy study Ann E. McDermott GS
1987 Structure of the manganese complex of photosystem II upon removal of the 33-kilodalton extrinsic protein: An X-ray absorption spectroscopy study Ann E. McDermott GS
1985 Electron transfer in photosystem II at cryogenic temperatures Gary Brudvig GS
1985 Segmental Flexibility of Receptor-Bound Immunoglobulin E Barbara A. Baird CV OA GS
1985 Structural Mapping of Fc Receptor Bound Immunoglobulin E: Proximity to the Membrane Surface of the Antibody Combining Site and Another Site in the Fab Segments Barbara A. Baird CV OA GS
1985 Structural Mapping of Membrane-Bound Immunoglobulin E-Receptor Complexes: Use of Monoclonal Anti-IgE Antibodies to Probe the Conformation of Receptor-Bound IgE Barbara A. Baird CV OA GS
1983 Structural studies on the membrane-bound immunoglobulin E (IgE)-receptor complex. 2. Mapping of distances between sites on IgE and the membrane surface Barbara A. Baird CV OA GS
1983 Structural studies on the membrane-bound immunoglobulin E-receptor complex. 1. Characterization of large plasma membrane vesicles from rat basophilic leukemia cells and insertion of amphipathic fluorescent probes Barbara A. Baird CV OA GS
1981 Conformations of oxidized cytochrome c oxidase Gary Brudvig GS
1980 Reactions of nitric oxide with cytochrome c oxidase Gary Brudvig GS