Publications

2025 Strategic modulation of polarity and viscosity sensitivity of bimane molecular rotor-based fluorophores for imaging α-synuclein E. James Petersson · bioRxiv · Scholar only 24 2024 Highly tunable bimane-based fluorescent probes: design, synthesis, and application as a selective amyloid binding dye E. James Petersson · Chemical Science · Scholar only 19 2024 Lanthanide binding peptide surfactants at air-aqueous interfaces for interfacial separation of rare earth elements E. James Petersson · Proceedings of the National Academy of Sciences · Scholar only 28 2024 The LexA–RecA* structure reveals a cryptic lock-and-key mechanism for SOS activation E. James Petersson · Nature structural & molecular biology · Scholar only 37 2023 AggBERT: best in class prediction of hexapeptide amyloidogenesis with a semi-supervised ProtBERT model E. James Petersson · Journal of chemical information and modeling · Scholar only 20 2023 A novel brain PET radiotracer for imaging alpha synuclein fibrils in multiple system atrophy E. James Petersson · Journal of Medicinal Chemistry · Scholar only 38 2023 Computational chemistry for the identification of lead compounds for radiotracer development E. James Petersson · Pharmaceuticals · Scholar only 33 2023 Global analysis of post-translational side-chain arginylation using pan-arginylation antibodies E. James Petersson · Molecular & Cellular Proteomics · Scholar only 16 2023 Identification of a Putative α-synuclein Radioligand Using an in silico Similarity Search E. James Petersson · Molecular imaging and biology · Scholar only 18 2023 Molecular role of NAA38 in thermostability and catalytic activity of the human NatC N-terminal acetyltransferase E. James Petersson · Structure 31 (2), 166-173. e4 · Scholar only 15 2023 Post-translational modifications of soluble α-synuclein regulate the amplification of pathological α-synuclein E. James Petersson · Nature neuroscience · Scholar only 146 2022 A bond-energy/bond-order and populations relationship E. James Petersson · Journal of Chemical Theory and Computation · Scholar only 22 2022 Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein E. James Petersson · Journal of the American Chemical Society · Scholar only 16 2022 Effects of mutations and post-translational modifications on α-synuclein in vitro aggregation E. James Petersson · Journal of Molecular Biology · Scholar only 58 2022 Generating efficient Methanomethylophilus alvus pyrrolysyl-tRNA synthetases for structurally diverse non-canonical amino acids E. James Petersson · ACS chemical biology · Scholar only 26 2022 Harnessing the intrinsic photochemistry of isoxazoles for the development of chemoproteomic crosslinking methods E. James Petersson · Chemical Communications · Scholar only 16 2022 Structural impact of thioamide incorporation into a β-hairpin E. James Petersson · RSC Chemical Biology · Scholar only 23 2022 α-Synuclein arginylation in the human brain E. James Petersson · Translational Neurodegeneration · Scholar only 21 2021 Alpha-synuclein from patient Lewy bodies exhibits distinct pathological activity that can be propagated in vitro E. James Petersson · Acta neuropathologica communications · Scholar only 94 2021 An improved fluorescent noncanonical amino acid for measuring conformational distributions using time-resolved transition metal ion FRET E. James Petersson · eLife · Scholar only 38 2021 Biomolecular simulation based machine learning models accurately predict sites of tolerability to the unnatural amino acid acridonylalanine E. James Petersson · Scientific Reports · Scholar only 18 2021 Chemoenzymatic Semi‐synthesis Enables Efficient Production of Isotopically Labeled α‐Synuclein with Site‐Specific Tyrosine Phosphorylation E. James Petersson · ChemBioChem · Scholar only 17 2021 Genetic encoding of a highly photostable, long lifetime fluorescent amino acid for imaging in mammalian cells E. James Petersson · Chemical science · Scholar only 61 2021 Insights into genome recoding from the mechanism of a classic+ 1-frameshifting tRNA E. James Petersson · Nature Communications · Scholar only 46 2021 New strategies for fluorescently labeling proteins in the study of amyloids E. James Petersson · Current opinion in chemical biology · Scholar only 46 2021 Rational design of thioamide peptides as selective inhibitors of cysteine protease cathepsin L E. James Petersson · Chemical Science · Scholar only 22 2021 Side‐chain thioamides as fluorescence quenching probes E. James Petersson · Biopolymers · Scholar only 16 2020 A unified de novo approach for predicting the structures of ordered and disordered proteins E. James Petersson · The journal of physical chemistry. B · Scholar only 32 2020 Chemoenzymatic Semisynthesis of Phosphorylated α-Synuclein Enables Identification of a Bidirectional Effect on Fibril Formation E. James Petersson · ACS Chemical Biology · Scholar only 44 2020 Evaluation of diagnostic accuracy following the coadministration of delta-aminolevulinic acid and second window indocyanine green in rodent and human glioblastomas E. James Petersson · Molecular imaging and biology · Scholar only 27 2020 Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening E. James Petersson · Chemical science · Scholar only 59 2020 Molecular basis for N-terminal alpha-synuclein acetylation by human NatB E. James Petersson · eLife · Scholar only 38 2020 Protein labeling for FRET with methoxycoumarin and acridonylalanine E. James Petersson · Methods in enzymology · Scholar only 22 2020 Rational design of small molecule fluorescent probes for biological applications E. James Petersson · Organic & biomolecular chemistry · Scholar only 314 2020 Rosetta custom score functions accurately predict ΔΔG of mutations at protein–protein interfaces using machine learning E. James Petersson · Chemical Communications · Scholar only 23 2020 Rosetta machine learning models accurately classify positional effects of thioamides on proteolysis E. James Petersson · The Journal of Physical Chemistry B · Scholar only 19 2020 Studies of thioamide effects on serine protease activity enable two-site stabilization of cancer imaging peptides E. James Petersson · ACS chemical biology · Scholar only 37 2020 Synthesis and characterization of high affinity fluorogenic α-synuclein probes E. James Petersson · Chemical Communications · Scholar only 47 2020 The Effects of Glutamate Arginylation on α-Synuclein: Studying an Unusual Post-translational Modification Through Semi-Synthesis E. James Petersson · Journal of the American Chemical Society · Scholar only 34 2020 The kinetic and molecular basis for the interaction of LexA and activated RecA revealed by a fluorescent amino acid probe E. James Petersson · ACS chemical biology · Scholar only 33 2019 A “clickable” photoconvertible small fluorescent molecule as a minimalist probe for tracking individual biomolecule complexes E. James Petersson · Journal of the American Chemical Society · Scholar only 58 2019 Biosynthesis and chemical applications of thioamides E. James Petersson · ACS chemical biology · Scholar only 237 2019 Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity E. James Petersson · Scientific Reports · Scholar only 48 2019 Fluorescent probes for studying thioamide positional effects on proteolysis reveal insight into resistance to cysteine proteases E. James Petersson · ChemBioChem · Scholar only 19 2019 Optimization of second window indocyanine green for intraoperative near-infrared imaging of thoracic malignancy E. James Petersson · Journal of the American College of Surgeons · Scholar only 76 2019 Structure and mechanism of acetylation by the N-terminal dual enzyme NatA/Naa50 complex E. James Petersson · Structure 27 (7), 1057-1070. e4 · Scholar only 53 2018 Alpha synuclein fibrils contain multiple binding sites for small molecules E. James Petersson · ACS chemical neuroscience · Scholar only 96 2018 Dithioamide substitutions in proteins: effects on thermostability, peptide binding, and fluorescence quenching in calmodulin E. James Petersson · Chemical Communications · Scholar only 31 2018 Fluorescence spectroscopy reveals N-terminal order in fibrillar forms of α-synuclein E. James Petersson · Chemical Communications · Scholar only 16 2018 Improving the fluorescent probe acridonylalanine through a combination of theory and experiment E. James Petersson · Journal of physical organic chemistry · Scholar only 29