Publications

2026 A class of metallohydrolases expands bile salt hydrolase activity in the gut Pamela Chang · bioRxiv · Scholar only — 2026 Chemical proteomics reveals regulation of bile salt hydrolases via oxidative post-translational modifications Pamela Chang · Journal of the American Chemical Society · Scholar only 4 2025 Chemoproteomic profiling of substrate specificity in gut microbiota-associated bile salt hydrolases Pamela Chang · Cell chemical biology 32 (1), 145-156. e9 · Scholar only 23 2025 Gut microbiota-mediated GPCR drug metabolism affects downstream pharmacological activity: Drug metabolism Pamela Chang · Nature Chemistry · Scholar only 1 2024 Bile Salt Hydrolase Activity‐Based Probes for Monitoring Gut Microbial Bile Acid Metabolism Pamela Chang · ChemBioChem · Scholar only 13 2024 Dopamine receptor D2 confers colonization resistance via microbial metabolites Pamela Chang · Nature · Scholar only 72 2024 Microbial metabolite-receptor interactions in the gut microbiome Pamela Chang · Current opinion in chemical biology · Scholar only 28 2023 Activity-based protein profiling in microbes and the gut microbiome Pamela Chang · Current opinion in chemical biology · Scholar only 15 2023 Chemoproteomic approaches for unraveling prokaryotic biology Pamela Chang · Israel journal of chemistry · Scholar only 6 2023 Electrostatic interactions dictate bile salt hydrolase substrate preference Pamela Chang · bioRxiv · Scholar only 11 2023 Shedding Light on Bacterial Physiology with Click Chemistry Pamela Chang · Israel journal of chemistry · Scholar only 5 2022 BSH-TRAP: Bile salt hydrolase tagging and retrieval with activity-based probes Pamela Chang · Methods in enzymology · Scholar only 6 2022 Deconvoluting host‐gut microbiota co‐metabolism Pamela Chang · The FASEB Journal · Scholar only — 2021 Compositions and methods for profiling of gut microbiota-associated bile salt hydrolase (bsh) activity Pamela Chang · US Patent App · Scholar only — 2020 Chemical mechanisms of colonization resistance by the gut microbial metabolome Pamela Chang · ACS chemical biology · Scholar only 46 2020 Engineered Th17 cell differentiation using a photoactivatable immune modulator Pamela Chang · Journal of the American Chemical Society · Scholar only 9 2020 Finding the Sweet Spot for Breast Cancer Detection Pamela Chang · ACS Central Science · Scholar only 1 2020 Microbial tryptophan metabolites regulate gut barrier function via the aryl hydrocarbon receptor Pamela Chang · Proceedings of the National Academy of Sciences · Scholar only 757 2019 Chemoproteomic profiling of gut microbiota-associated bile salt hydrolase activity Pamela Chang · ACS central science · Scholar only 104 2019 Deciphering the chemical lexicon of host–gut microbiota interactions Pamela Chang · Trends in pharmacological sciences · Scholar only 218 2018 Designer Dendrons To Dissect Innate Immune Signaling Pamela Chang · ACS Central Science · Scholar only — 2017 Chemical optogenetic modulation of inflammation and immunity Pamela Chang · Chemical Science · Scholar only 24 2014 The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition Pamela Chang · Proceedings of the National Academy of Sciences · Scholar only 2,647 2012 Imaging beyond the proteome Pamela Chang · Chemical Communications · Scholar only 99 2010 A strategy for the selective imaging of glycans using caged metabolic precursors Pamela Chang · Journal of the American Chemical Society · Scholar only 120 2010 Chemical Tools for Imaging Glycans in Living Systems Pamela Chang · UC Berkeley · Scholar only — 2010 Copper-free click chemistry in living animals Pamela Chang · Proceedings of the National Academy of Sciences · Scholar only 873 2009 Metabolic labeling of sialic acids in living animals with alkynyl sugars Pamela Chang · Angewandte Chemie International Edition · Scholar only 274 2009 Photoaffinity Isolation and Identification of Proteins in Cancer Cell Extracts that Bind to Platinum‐Modified DNA Pamela Chang · ChemBioChem · Scholar only 89 2008 Polysialic acid, a glycan with highly restricted expression, is found on human and murine leukocytes and modulates immune responses Pamela Chang · The Journal of Immunology · Scholar only 127 2007 Copper-free click chemistry for dynamic in vivo imaging Pamela Chang · Proceedings of the National Academy of Sciences · Scholar only 2,550 2007 Imaging cell surface glycans with bioorthogonal chemical reporters Pamela Chang · Journal of the American Chemical Society · Scholar only 257 2006 Metabolic labeling of glycans with azido sugars for visualization and glycoproteomics Pamela Chang · Methods in enzymology · Scholar only 208 2004 Identification of nuclear proteins that interact with platinum-modified DNA by photoaffinity labeling Pamela Chang · Journal of the American Chemical Society · Scholar only 77