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Publications

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2025 Drug binding disrupts chiral water structures in the DNA first hydration shell E. Chui-Ying Yan · Chemical Science 7 2024 Beyond the ‘Spine of Hydration’: Chiral SFG Spectroscopy Detects DNA First Hydration Shell and Base Pair Structures E. Chui-Ying Yan · The Journal of Chemical Physics 15 2024 Theoretical basis for interpreting heterodyne chirality-selective sum frequency generation spectra of water E. Chui-Ying Yan · The Journal of Chemical Physics 8 2024 Water-protein interactions as a driver of phase separation, biology, and disease E. Chui-Ying Yan · Biophysical Journal 4 2023 Characterizing interfaces by Voronai tessellation E. Chui-Ying Yan · The Journal of Physical Chemistry Letters 15 2023 Design of an Electrostatic Frequency Map for the NH Stretch of the Protein Backbone and Application to Chiral Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · The Journal of Physical Chemistry B 17 2023 Detecting interplay of chirality, water, and interfaces for elucidating biological functions E. Chui-Ying Yan · Accounts of Chemical Research 23 2022 Chiral Sum Frequency Generation Spectroscopy Detects Double-Helix DNA at Interfaces E. Chui-Ying Yan · Langmuir 19 2022 Detecting the first hydration shell structure around biomolecules at interfaces E. Chui-Ying Yan · ACS Central Science 67 2021 Simulation of the Chiral Sum Frequency Generation Response of Supramolecular Structures Requires Vibrational Couplings E. Chui-Ying Yan · The Journal of Physical Chemistry B 20 2020 Impact of the Emergency Transition to Remote Teaching on Student Engagement in a Non-STEM Undergraduate Chemistry Course in the Time of COVID-19 E. Chui-Ying Yan · Journal of Chemical Education 148 2020 Mirror-image antiparallel ·-sheets organize water molecules into superstructures with opposite chirality E. Chui-Ying Yan · Proceedings of the National Academy of Sciences 43 2019 Chiral Inversion of Amino Acids in Anti-Parallel β-sheets Probed by Vibrational Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · The Journal of Physical Chemistry B 31 2019 Chiral Water Superstructures around Antiparallel β‑Sheets Observed by Chiral Vibrational Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · The Journal of Physical Chemistry Letters 45 2018 Calcium sensing ability of parathyroid hormone uncovers new mechanism for family B GPCR signaling E. Chui-Ying Yan · ACS Chem. Biol. 2018 Two dimensional crowding effects on protein folding at interfaces observed by chiral vibrational sum frequency generation spectroscopy E. Chui-Ying Yan · Physical Chemistry Chemical Physics 25 2017 Characterization of Surface-Active Biofilm Protein BslA in Self-Assembling Langmuir Monolayer at the Air-Water Interface E. Chui-Ying Yan · Langmuir 17 2017 Flat Drops, Elastic Sheets, and Microcapsules by Interfacial Assembly of a Bacterial Biofilm Protein, BslA E. Chui-Ying Yan · Langmuir 14 2017 Probing the Remarkable Thermal Kinetics of Visual Rhodopsin with E181Q and S186A Mutants E. Chui-Ying Yan · The Journal of Chemical Physics 6 2017 Protein Sequence and Membrane Lipid Roles in the Activation Kinetics of Bovine and Human Rhodopsins E. Chui-Ying Yan · Biophysical Journal 8 2017 Purification of family B G protein-coupled receptors using nanodiscs: Application to human glucagon-like peptide-1 receptor E. Chui-Ying Yan · PLOS ONE 30 2017 The H2O Helix: The Chiral Water Superstructure Surrounding DNA E. Chui-Ying Yan · ACS Central Science 31 2016 Fabrication of Modularly Functionalizable Microcapsules Using Protein-Based Technologies E. Chui-Ying Yan · ACS Biomaterials Science & Engineering 24 2016 Homodimerization enhances both sensitivity and dynamic range of the ligand-binding domain of type 1 metabotropic glutamate receptor E. Chui-Ying Yan · FEBS Letters 4 2016 New Insights from Sum Frequency Generation Vibrational Spectroscopy into the Interactions of Islet Amyloid Polypeptides with Lipid Membranes E. Chui-Ying Yan · Journal of Diabetes Research 28 2016 Structural role of the T94I rhodopsin mutation in congenital stationary night blindness E. Chui-Ying Yan · The EMBO Reports 41 2016 Vibrational Sum Frequency Generation Spectroscopy Reveals Highly Ordered Structures of a Biofilm Protein at the Air/Water Interface E. Chui-Ying Yan · Chemical Communications 27 2015 Broad-Bandwidth Chiral Sum Frequency Generation Spectroscopy for Probing the Kinetics of Proteins at Interfaces E. Chui-Ying Yan · Langmuir 18 2015 Characterization of Parallel β-Sheets at Interfaces by Chiral Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · The Journal of Physical Chemistry Letters 41 2015 Kinetics of Thermal Activation of an Ultraviolet Cone Pigment E. Chui-Ying Yan · Journal of the American Chemical Society 7 2015 Proteins at Interfaces Probed by Chiral Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · The Journal of Physical Chemistry B 78 2015 Transmembrane signal transduction by peptide hormones via family B G protein-coupled receptors E. Chui-Ying Yan · Frontiers in Pharmacology 76 2015 Triblock Peptide-Linker-Lipid Molecular Design Improves Potency of Peptide Ligands Targeting Family B G Protein-Coupled Receptors E. Chui-Ying Yan · Chemical Communications 10 2014 Assignment of Protein N-H Stretching Modes Observed by Chiral Sum frequency Generation Spectroscopy to Peptide Backbone E. Chui-Ying Yan · Chirality 31 2014 Biological Macromolecules at Interfaces Probed by Chiral Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · Chemical Reviews 298 2014 Role of Unusual Temperature-Dependent Kinetics of Thermal Reactions of Rhodopsin in Vertebrate Dim-Light Vision E. Chui-Ying Yan · Proc. Natl. Acad. Sci. U.S.A. · needs review 2013 Calcium-Dependent Ligand Binding and G-protein Signaling of Family B GPCR Parathyroid Hormone 1 Receptor Purified in Nanodiscs E. Chui-Ying Yan · ACS Chemical Biology 40 2013 Chiral Sum Frequency Generation for In Situ Probing Proton Exchange in Antiparallel β-Sheet Peptides at Interfaces E. Chui-Ying Yan · Journal of the American Chemical Society 88 2013 C-H Stretch for Probing Self-Assembly of LK7β into Chiral Macromolecular Structures at the Air-Water Interface by Chiral Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · Langmuir 42 2013 Guided Inquiry and Project-Based Learning in Biophysical Spectroscopy E. Chui-Ying Yan · ACS Symposium Series 2 2013 Lipid Compositions Modulate Fluidity and Stability of Bilayers: Characterization by Surface Pressure and Sum Frequency Generation Spectroscopy E. Chui-Ying Yan · Langmuir 58 2013 Spectral Tuning of Ultraviolet Cone Pigments: An Interhelical Lock Mechanism E. Chui-Ying Yan · Journal of the American Chemical Society 24 2013 Thermal Stability of Rhodopsin and Progression of Retinitis Pigmentosa: A Comparison of S186W and D190N Rhodopsin Mutants E. Chui-Ying Yan · Journal of Biological Chemistry 34 2012 Amphiphilic Adsorption of Human Islet Amyloid Polypeptide Aggregates to Lipid/Aqueous Interfaces E. Chui-Ying Yan · Journal of Molecular Biology 80 2012 Rational Design of Supramolecular Lipid/Detergent Assemblies for Purification of G Protein-Coupled Receptors E. Chui-Ying Yan · Encyclopedia of Supramolecular Chemistry 2012 Real time kinetics of surfactant molecules transfer between emulsion particles probed by in situ second harmonic generation spectroscopy E. Chui-Ying Yan · Journal of the American Chemical Society 33 2012 Schiff base protonation changes in siberian hamster ultraviolet cone pigment photointermediates E. Chui-Ying Yan · Biochemistry 22 2011 Artificial Membrane-like Environments for In Vitro Studies of Purified G-protein Coupled Receptors E. Chui-Ying Yan · Biochimica et Biophysica Acta (BBA) - Biomembranes 101 2011 Chemical Kinetic Analysis of Thermal Decay of Rhodopsin Reveals Unusual Energetics of Thermal Isomerization and Hydrolysis of Schiff Base E. Chui-Ying Yan · Journal of Biological Chemistry 12 2011 Chiral Sum Frequency Generation Spectroscopy for Characterizing Protein Secondary Structures at Interfaces E. Chui-Ying Yan · Journal of the American Chemical Society 264
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2025 · article · journal

Drug binding disrupts chiral water structures in the DNA first hydration shell

Chemical Science · Sharon Hammes-SchifferE. Chui-Ying Yan

in CV in OpenAlex
noneScholar citations
7OpenAlex citations

From the CV · Sharon Hammes-Schiffer

lines 1603–1605 · published

393. T. Santiago, D. Konstantinovsky, M. Tremblay, E. A. Perets, S. Hammes-Schiffer, and E.C. Y. Yan, ·Drug binding disrupts chiral water structures in the DNA first hydration shell,·Chem. Sci. 16, 6853-6861 (2025).

Peer reviewed
yes
First author
Santiago
Co-authors
T. Santiago; D. Konstantinovsky; M. Tremblay; E. A. Perets; S. Hammes-Schiffer; E. C. Y. Yan
Subfield
other
Method
none
Invited
none
Publisher
none
Reprint or translation
none

From the CV · E. Chui-Ying Yan

lines 144–146 · published

1.​ Santiago, T.†; Konstantinovsky, D.†; Tremblay, M.†; Perets, E.*; Hammes-Schiffer, S.*; Yan, E. C. Y.*"Drug binding disrupts chiral water structures in the DNA first hydration shell" Chem. Sci., 16,6853-6861, 2025.

Peer reviewed
yes
First author
Santiago
Co-authors
Santiago, T.†; Konstantinovsky, D.†; Tremblay, M.†; Perets, E.*; Hammes-Schiffer, S.*; Yan, E. C. Y.*
Subfield
other
Method
none
Invited
none
Publisher
none
Reprint or translation
none
DOI
10.1039/d4sc08372e
OpenAlex
W4408403238

Where each field came from

FieldCVOpenAlexScholarCrossRef
title Drug binding disrupts chiral water structures in the DNA first hydration shell (used)Drug binding disrupts chiral water structures in the DNA first hydration shellDrug binding disrupts chiral water structures in the DNA first hydration shell
year 2025 (used)20252025
venue Chem. Sci.Chem. Sci.Chemical ScienceChemical Science (used)
kind article (used)articlearticle
DOI 10.1039/d4sc08372e (used)10.1039/d4sc08372e10.1039/d4sc08372e
first author SantiagoSantiagoSantiago (used)

The value in bold is the one the record uses.

How the records were joined

  • gemini merged · 1.00 · Run 18The CV record and OpenAlex record share the exact same DOI and title regarding drug binding and chiral water structures.