Publications

2025 Structural Insights into the Role of the Proline Rich Region in Tau Function Elizabeth Rhoades · Structure · Scholar only 12 2024 Multivalency drives interactions of alpha-synuclein fibrils with tau Elizabeth Rhoades · PLoS One · Scholar only 12 2024 Sequential CRISPR screening reveals partial NatB inhibition as a strategy to mitigate alpha-synuclein levels in human neurons. Elizabeth Rhoades · Science Advances 10 (6), eadj4767 · Scholar only 20 2024 Simple detection of submicroscopic protein clusters with a phase-separation-based fluorescent reporter Elizabeth Rhoades · Cell Systems · Scholar only 23 2023 Combining non-canonical amino acid mutagenesis and native chemical ligation for multiply modifying proteins: A case study of α-synuclein post-translational modifications Elizabeth Rhoades · Methods · Scholar only 5 2023 Semi-Synthetic CoA-α-Synuclein Constructs Trap N-Terminal Acetyltransferase NatB for Binding Mechanism Studies Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 6 2023 The C-terminus of α-Synuclein Regulates its Dynamic Cellular Internalization by Neurexin 1β Elizabeth Rhoades · Molecular Biology of the Cell · Scholar only 10 2023 The Effects of Lipids on α-Synuclein Aggregation In Vitro. Elizabeth Rhoades · Biomolecules · Scholar only 14 2022 Cysteine-Based Mimic of Arginylation Reproduces Neuroprotective Effects of the Authentic Post-Translational Modification on α-Synuclein Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 16 2022 The N-terminal disease–associated R5L Tau mutation increases microtubule shrinkage rate due to disruption of microtubule-bound Tau patches Elizabeth Rhoades · Journal of Biological Chemistry · Scholar only 3 2022 α-Synuclein arginylation in the human brain Elizabeth Rhoades · Translational Neurodegeneration · Scholar only 21 2021 Chemoenzymatic Semi‐synthesis Enables Efficient Production of Isotopically Labeled α‐Synuclein with Site‐Specific Tyrosine Phosphorylation Elizabeth Rhoades · ChemBioChem · Scholar only 17 2021 Potent inhibitors of toxic alpha-synuclein identified via cellular time-resolved FRET biosensors Elizabeth Rhoades · npj Parkinson's Disease · Scholar only 39 2020 Chemoenzymatic Semisynthesis of Phosphorylated α-Synuclein Enables Identification of a Bidirectional Effect on Fibril Formation Elizabeth Rhoades · ACS Chemical Biology · Scholar only 44 2020 Effects of Glutamate Arginylation on α-Synuclein: Studying an Unusual Post-Translational Modification through Semisynthesis Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 34 2020 Measuring interactions between tau and aggregation inducers with single-molecule Förster resonance energy transfer Elizabeth Rhoades · Intrinsically Disordered Proteins: Methods and Protocols · Scholar only 8 2020 Quantification of protein delivery in live cells using fluorescence correlation spectroscopy Elizabeth Rhoades · Methods in Enzymology · Scholar only 14 2020 Single-molecule FRET of intrinsically disordered proteins Elizabeth Rhoades · Annual review of physical chemistry · Scholar only 120 2020 Structural Characterization of Tau in Fuzzy Tau:Tubulin Complexes Elizabeth Rhoades · Structure · Scholar only 20 2020 Tau Avoids the GTP Cap at Growing Microtubule Plus-Ends Elizabeth Rhoades · Iscience · Scholar only 29 2019 Cyclized NDGA modifies dynamic α-synuclein monomers preventing aggregation and toxicity Elizabeth Rhoades · Scientific Reports · Scholar only 48 2019 Identification of N-linked glycans as specific mediators of neuronal uptake of acetylated α-Synuclein Elizabeth Rhoades · PLoS Biology · Scholar only 77 2019 Independent tubulin binding and polymerization by the proline-rich region of Tau is regulated by Tau's N-terminal domain Elizabeth Rhoades · Journal of Biological Chemistry · Scholar only 67 2019 Polyphosphate initiates tau aggregation through intra- and intermolecular cross-linking Elizabeth Rhoades · Biophysical Journal · Scholar only 64 2019 Proteins: Disorder, Folding, and Crowding Elizabeth Rhoades · Biophysical journal · Scholar only 1 2019 Targeting the ensemble of heterogeneous tau oligomers in cells: A novel small molecule screening platform for tauopathies Elizabeth Rhoades · Alzheimer's & Dementia · Scholar only 72 2018 Conformational changes in Arp2/3 complex induced by ATP, WASp-VCA, and actin filaments Elizabeth Rhoades · Proceedings of the National Academy of Sciences · Scholar only 77 2018 Conformational switching within dynamic oligomers underpins toxic gain-of-function by diabetes-associated amyloid Elizabeth Rhoades · Nature communications · Scholar only 72 2018 IDPs in macromolecular complexes: the roles of multivalent interactions in diverse assemblies Elizabeth Rhoades · Current opinion in structural biology · Scholar only 180 2018 Intrinsically Disordered Proteins Elizabeth Rhoades · Academic Press · Scholar only 13 2018 Targeting the Intrinsically Disordered Proteome Using Small-Molecule Ligands. Elizabeth Rhoades · Methods in enzymology · Scholar only 24 2018 Unique arginine array improves cytosolic localization of hydrocarbon-stapled peptides Elizabeth Rhoades · Bioorganic & medicinal chemistry · Scholar only 21 2018 Using a FRET library with multiple probe pairs to drive monte carlo simulations of α-synuclein Elizabeth Rhoades · Biophysical journal · Scholar only 31 2017 Heterogeneous tau-tubulin complexes accelerate microtubule polymerization Elizabeth Rhoades · Biophysical journal · Scholar only 51 2017 Insights into tau function and dysfunction through single-molecule fluorescence Elizabeth Rhoades · Methods in cell biology · Scholar only 22 2017 α-Synuclein’s uniquely long amphipathic helix enhances its membrane binding and remodeling capacity Elizabeth Rhoades · The Journal of membrane biology · Scholar only 43 2016 A functional role for intrinsic disorder in the tau-tubulin complex Elizabeth Rhoades · Proceedings of the National Academy of Sciences · Scholar only 95 2016 Foldamer-mediated manipulation of a pre-amyloid toxin Elizabeth Rhoades · Nature communications · Scholar only 82 2016 Membrane remodeling and mechanics: Experiments and simulations of α-Synuclein Elizabeth Rhoades · Biochimica et Biophysica Acta (BBA)-Biomembranes · Scholar only 63 2016 Order–Disorder Transitions in the Cardiac Troponin Complex Elizabeth Rhoades · Journal of Molecular Biology · Scholar only 32 2016 Two Na+ sites control conformational change in a neurotransmitter transporter homolog Elizabeth Rhoades · Journal of Biological Chemistry · Scholar only 87 2015 Biophysics of α-synuclein induced membrane remodelling Elizabeth Rhoades · Physical Chemistry Chemical Physics · Scholar only 76 2015 Conformation and Dynamics of the Troponin I C-Terminal Domain: Combining Single-Molecule and Computational Approaches for a Disordered Protein Region Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 68 2015 Cross-Scale Integrin Regulation Organizes ECM and Tissue Topology Elizabeth Rhoades · Developmental cell · Scholar only 109 2015 Fluorescence Correlation Spectroscopy Reveals Highly Efficient Cytosolic Delivery of Certain Penta-Arg Proteins and Stapled Peptides Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 172 2015 Folding upon phosphorylation: translational regulation by a disorder-to-order transition Elizabeth Rhoades · Trends in biochemical sciences · Scholar only 12 2015 Islet amyloid-induced cell death and bilayer integrity loss share a molecular origin targetable with oligopyridylamide-based α-helical mimetics Elizabeth Rhoades · Chemistry & biology · Scholar only 74 2015 Physico-chemical requirements and kinetics of membrane fusion of flavivirus-like particles Elizabeth Rhoades · Journal of General Virology · Scholar only 43 2015 Structure-based small molecule modulation of a pre-amyloid state: pharmacological enhancement of iapp membrane-binding and toxicity Elizabeth Rhoades · Biochemistry · Scholar only 15 2015 Tau binds to multiple tubulin dimers with helical structure Elizabeth Rhoades · Journal of the American Chemical Society · Scholar only 77