Publications

2011 Trifluoroacetic anhydride-catalyzed oxidation of isonitriles by DMSO: A rapid, convenient synthesis of isocyanates Bruce Ganem · Organic letters · Scholar only 63 2010 Dihydropyrimidinone positive modulation of δ-subunit-containing γ-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant Bruce Ganem · Biochemistry · Scholar only 122 2009 Strategies for innovation in multicomponent reaction design Bruce Ganem · Accounts of chemical research · Scholar only 1,404 2007 Paclitaxel from primary taxanes: a perspective on creative invention in organozirconium chemistry Bruce Ganem · The Journal of Organic Chemistry · Scholar only 87 2006 Studies on the Biginelli reaction: a mild and selective route to 3, 4-dihydropyrimidin-2 (1H)-ones via enamine intermediates Bruce Ganem · Tetrahedron letters · Scholar only 119 2004 Three-component condensation leading to β-amino acid diamides: convergent assembly of β-peptide analogues Bruce Ganem · Journal of the American Chemical Society · Scholar only 54 2003 3‐Trimethylsilyl‐3‐Buten‐2‐one: AM ichael acceptor: 3‐Buten‐2‐one, 3‐(trimethylsilyl)‐ Bruce Ganem · Organic Syntheses · Scholar only 82 2003 A general synthesis of 2-substituted-5-aminooxazoles: building blocks for multifunctional heterocycles Bruce Ganem · Tetrahedron letters · Scholar only 51 2003 Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts Bruce Ganem · Journal of the American Chemical Society · Scholar only 78 2002 An efficient synthesis of substituted prolines by the selective reduction and reductive cyanation of 2-pyrrolidones Bruce Ganem · Tetrahedron letters · Scholar only 59 2002 Metal-promoted variants of the Passerini reaction leading to functionalized heterocycles Bruce Ganem · Organic Letters · Scholar only 94 2002 Total synthesis of (-)-vertinolide. A general approach to chiral tetronic acids and butenolides from allylic alcohols Bruce Ganem · The Journal of Organic Chemistry · Scholar only 100 2001 Asymmetric total synthesis of (−)-α-kainic acid using an enantioselective, metal-promoted ene cyclization Bruce Ganem · Organic Letters · Scholar only 141 2001 Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents Bruce Ganem · Bioorganic & medicinal chemistry letters · Scholar only 77 2001 Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate Bruce Ganem · Organic Letters · Scholar only 66 2000 A new synthesis of the glyoxalase-I inhibitor COTC Bruce Ganem · Tetrahedron Letters · Scholar only 51 2000 Probing the Catalytic Mechanism of Prephenate Dehydratase by Site-Directed Mutagenesis of the Escherichia coli P-Protein Dehydratase Domain Bruce Ganem · Biochemistry · Scholar only 62 2000 Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor Bruce Ganem · Organic Letters · Scholar only 64 1999 Regulation of Phenylalanine Biosynthesis. Studies on the Mechanism of Phenylalanine Binding and Feedback Inhibition in the Escherichia coli P-Protein Bruce Ganem · Biochemistry · Scholar only 65 1999 Structure and Total Synthesis of HF-7, a Neuroactive Glyconucleoside Disulfate from the Funnel-Web Spider Hololena curta Bruce Ganem · Journal of the American Chemical Society · Scholar only 91 1998 Chorismate mutase-prephenate dehydratase from Escherichia coli: study of catalytic and regulatory domains using genetically engineered proteins Bruce Ganem · Journal of Biological Chemistry · Scholar only 141 1998 Enantioselective approaches to aminocyclopentitols: A total synthesis of (+)-6-epitrehazolin and a formal total synthesis of (+)-trehazolin Bruce Ganem · The Journal of Organic Chemistry · Scholar only 53 1998 Pseudoceratidine, a marine natural product with antifouling activity: synthetic and biological studies Bruce Ganem · Tetrahedron · Scholar only 69 1997 A new approach to porphobilinogen and its analogs Bruce Ganem · Tetrahedron · Scholar only 133 1996 Characterization of Benzodiazepine “Combinatorial” Chemical Libraries by On-Line Immunoaffinity Extraction, Coupled Column HPLC− Ion Spray Mass Spectrometry− Tandem Mass … Bruce Ganem · Analytical chemistry · Scholar only 140 1996 Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors Bruce Ganem · Bioorganic & Medicinal Chemistry · Scholar only 89 1996 Identification of two functionally different classes of exocellulases Bruce Ganem · Biochemistry · Scholar only 392 1996 Inhibitors of carbohydrate-processing enzymes: Design and synthesis of sugar-shaped heterocycles Bruce Ganem · Accounts of chemical research · Scholar only 362 1996 Reduction of secondary carboxamides to imines Bruce Ganem · The Journal of Organic Chemistry · Scholar only 116 1996 Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein Bruce Ganem · Bioorganic & Medicinal Chemistry · Scholar only 59 1996 The mechanism of the Claisen rearrangement: déjà vu all over again Bruce Ganem · Angewandte Chemie International Edition in English · Scholar only 169 1995 Atomic structure of the buried catalytic pocket of Escherichia coli chorismate mutase Bruce Ganem · Journal of the American Chemical Society · Scholar only 300 1995 Kinetic monitoring of enzymatic reactions in real time by quantitative high-performance liquid chromatography-mass spectrometry Bruce Ganem · Analytical biochemistry · Scholar only 68 1995 Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase Bruce Ganem · Biochemical Journal · Scholar only 110 1995 New insight into the catalytic mechanism of chorismate mutases from structural studies Bruce Ganem · Chemistry & biology · Scholar only 166 1995 Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry Bruce Ganem · Journal of Mass Spectrometry · Scholar only 175 1995 Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. Bruce Ganem · Journal of lipid research · Scholar only 235 1994 Analysis of the energetics of gas-phase immunophilin-ligand complexes by ion spray mass spectrometry Bruce Ganem · Journal of the American Chemical Society · Scholar only 66 1994 Studies of non‐covalent interactions of actinomycin D with single‐stranded oligodeoxynucleotides by ion spray mass spectrometry and tandem mass spectrometry Bruce Ganem · Biological mass spectrometry · Scholar only 84 1994 Studies on morpholinosphingolipids: potent inhibitors of glucosylceramide synthase Bruce Ganem · Elsevier · Scholar only 81 1994 Synthetic studies on Mannostatin A and its derivatives: a new family of glycoprotein processing inhibitors Bruce Ganem · Journal of the American Chemical Society · Scholar only 115 1993 Amidine, amidrazone, and amidoxime derivatives of monosaccharide aldonolactams: synthesis and evaluation as glycosidase inhibitors Bruce Ganem · Journal of the American Chemical Society · Scholar only 156 1993 Detecting noncovalent complexes of biological macromolecules: new applications of ion-spray mass spectrometry Bruce Ganem · Chemtracts: Org. Chem · Scholar only 52 1993 Detection of oligonucleotide duplex forms by ion-spray mass spectrometry Bruce Ganem · Tetrahedron letters · Scholar only 180 1993 Mass spectrometric studies on noncovalent dimers of leucine zipper peptides Bruce Ganem · Journal of the American Chemical Society · Scholar only 128 1993 Reductive deoxygenation by Cp2ZrHCl: Selective formation of imines via zirconation/hydrozirconation of amides Bruce Ganem · Tetrahedron letters · Scholar only 100 1993 Studies on heme binding in myoglobin, hemoglobin, and cytochrome c by ion spray mass spectrometry Bruce Ganem · Journal of the American Society for Mass Spectrometry · Scholar only 160 1992 Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-l-methionine decarboxylase inhibitor 5′-([(Z)-4-amino-2-butenyl]methylamino)-5 … Bruce Ganem · Biochemical Journal · Scholar only 111 1991 Detection of noncovalent receptor-ligand complexes by mass spectrometry Bruce Ganem · Journal of the American Chemical Society · Scholar only 741 1991 Enantioselective synthesis of mannostatin A: a new glycoprotein processing inhibitor Bruce Ganem · Journal of the American Chemical Society · Scholar only 75