Publications

2025 Bidirectional histone monoaminylation dynamics regulate neural rhythmicity Tom Muir · Nature · Scholar only 71 2025 Native nucleosomes intrinsically encode genome organization principles Tom Muir · Nature · Scholar only 37 2023 A genetically encoded photoproximity labeling approach for mapping protein territories Tom Muir · Proceedings of the National Academy of Sciences · Scholar only 92 2023 Tracking chromatin state changes using nanoscale photo-proximity labeling Tom Muir · Nature · Scholar only 130 2022 Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation Tom Muir · Molecular Cell · Scholar only 42 2022 Reconstitution of the S. aureus agr quorum sensing pathway reveals a direct role for the integral membrane protease MroQ in pheromone biosynthesis Tom Muir · Proceedings of the National Academy of Sciences · Scholar only 52 2022 TGM2-mediated histone transglutamination is dictated by steric accessibility Tom Muir · Proceedings of the National Academy of Sciences · Scholar only 45 2021 Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes. Tom Muir · Science 146 2021 Dot1L Complex Regulates Transcriptional Initiation in Human Erythroleukemic Cells Tom Muir · Proceedings of the National Academy of Sciences 73 2021 Engineering of a peptide α-N-methyltransferase to methylate non-proteinogenic amino acids Tom Muir · Angewandte Chemie International Edition 19 2021 Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout Tom Muir · Proceedings of the National Academy of Sciences 104 2021 Molecular Epigenetics: Chemical Biology Tools Come of Age Tom Muir · Annual Review of Biochemistry 19 2021 Oncohistone mutations enhance chromatin remodeling and alter cell fate Tom Muir · Nature Chemical Biology 113 2021 Reactive Intermediates for Interactome Mapping Tom Muir · Chemical Society Reviews 111 2021 Synthesis of ADP-Ribosylated Histones Reveals Site-Specific Impacts on Chromatin Structure and Function Tom Muir · Journal of the American Chemical Society · Scholar only 58 2020 A basic motif anchoring ISWI to the nucleosome acidic patch regulates nucleosome spacing Tom Muir · Nature Chemical Biology 96 2020 A nucleosome acidic patch binder stabilized by UbH2A underlies cancer-specific mSWI/SNF chromatin remodeling activities Tom Muir · Nature Structure and Molecular Biology — 2020 Bisphosphoglycerate Mutase Deficiency Protects against Cerebral Malaria and Severe Malaria-Induced Anemia Tom Muir · Cell Reports 12 2020 Cancer-associated Mutations in ENL Drive Self-reinforced Chromatin Targeting and Impair Cell Differentiation Tom Muir · Nature — 2020 Chemoenzymatic semisynthesis of proteins Tom Muir · Chemical Reviews 261 2020 Chromatin as a key consumer in the metabolic economy Tom Muir · Nature Chemical Biology 94 2020 Discovery of quorum quenchers targeting the membrane-embedded sensor domain of the Staphyloccocus aureus receptor histidine kinase, AgrC. Tom Muir · Chemical Communications 27 2020 H2B ubiquitylation enhances H3K4 methylation activities of human KMT2 family complexes Tom Muir · Nucleic Acids Research 51 2020 In situ chromatin interactomics using a chemical bait & trap approach Tom Muir · Nature Chemistry 83 2020 Live-cell protein engineering with an ultra-short split intein Tom Muir · Proceedings of the National Academy of Sciences 75 2020 Single-molecule and in silico dissection of the of the interaction between Polycomb repressive complex 2 and chromatin Tom Muir · Proceedings of the National Academy of Sciences 51 2020 The chaperone FACT and histone H2B ubiquitination maintain S. pombe genome architecture through genic and subtelomeric functions Tom Muir · Molecular Cell 54 2020 The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma Tom Muir · Nature Structural & Molecular Biology · Scholar only 75 2019 Determining the Spheroid Geometry of Individual Metallic Nanoparticles by Two-Dimensional Single-Particle Dynamic Light Scattering Tom Muir · The Journal of Physical Chemistry C 5 2019 Glutamine 5 serotonylation in histone H3 is a permissive modification that functions combinatorially with H3K4me3 to potentiate TFIID interactions Tom Muir · Nature 560 2019 Identification of a DNA methyltransferase complex and the impact of N6-methyladenine on chromatin organization Tom Muir · Cell 120 2019 Identification of a Molecular Latch that Regulates Staphylococcal Virulence Tom Muir · Cell Chemical Biology 30 2019 Impaired cell fate through gain-of-function mutations in a chromatin reader Tom Muir · Nature · Scholar only 163 2019 Intellectual disability-associated mutations in SMARCB1 reveal a conserved coiled-coil nucleosome interaction that potentiates mSWI/SNF chromatin remodeling Tom Muir · Cell 138 2019 JASPer controls interphase H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila Tom Muir · Nature Communications 31 2019 Nucleation and propagation of heterochromatin by the histone methyltransferase PRC2: geometric constraints and impact of the regulatory subunit JARID2 Tom Muir · Journal of the American Chemical Society 26 2019 Nucleic acid-barcoding technologies: converting DNA sequencing into a broad-spectrum molecular counter Tom Muir · Angewandte Chemie International Edition 39 2019 PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism Tom Muir · Nature Communications 258 2019 Phosphohistidine mimetics and Antibodies to Same Tom Muir · US 10, 351,581, issued July 16, 2019 — 2019 PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor Tom Muir · Proceedings of the National Academy of Sciences 47 2019 Protein Engineering through Tandem Transamidation Tom Muir · Nature Chemistry 44 2019 Proximity Induced Splicing Utilizing Caged Split Inteins Tom Muir · Journal of the American Chemical Society 27 2019 Single-Particle Dynamic Light Scattering: Shapes of Individual Nanoparticles. Tom Muir · Nano Letters 43 2019 The expanding landscape of ‘oncohistone’ mutations in human cancers Tom Muir · Nature 447 2019 The histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase Tom Muir · Proceedings of the National Academy of Sciences 123 2018 Acetylation blocks DNA damage-induced chromatin ADP-ribosylation Tom Muir · Nature Chemical Biology 102 2018 A Chemical Probe for Protein Crotonylation Tom Muir · Journal of the American Chemical Society 81 2018 An Atypical Mechanism of Split Intein Molecular Recognition and Folding Tom Muir · Journal of the American Chemical Society 30 2018 Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation Tom Muir · Nucleic Acids Research 27 2018 DNA barcoding of designer mononucleosome and chromatin array libraries Tom Muir · US 10,087,485, issued October 2, 2018 —