Publications

2026 Cellular repair and removal of protein damage modifications Christina Woo · Annual Review of Biochemistry — 2026 Identification of an allosteric site on the E3 ligase adapter cereblon Christina Woo · Nature — 2026 Small molecule splicing modulators that disrupt O-GlcNAc homeostasis Christina Woo · Nature Communications — 2026 The Contribution of Native Protein Complexes to Targeted Protein Degradation Christina Woo · ACS Chemical Biology 3 2025 A method for the detection and enrichment of endogenous cereblon substrates Christina Woo · Cell Chemical Biology 8 2025 Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer Christina Woo · Nature Cell Biology 24 2025 Enzyme-Activated Sugar-Coated Bifunctional Degraders Christina Woo · Journal of the American Chemical Society 21 2025 Genesis and regulation of C-terminal cyclic imides from protein damage Christina Woo · Proceedings of the National Academy of Sciences 23 2025 Investigation of glutarimide N-alkylated derivatives of lenalidomide Christina Woo · ACS Chemical Biology 2 2025 PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates Christina Woo · Nature Chemical Biology 12 2025 Probing the E3 Ligase Adapter Cereblon with Chemical Biology Christina Woo · Accounts of Chemical Research 4 2025 Targeted protein O-GlcNAc reveals transcriptional functions for O-GlcNAc Christina Woo · Cell Chemical Biology 5 2025 The contribution of cyclic imide stereoisomers on cereblon-dependent activity Christina Woo · Chemical Science 8 2024 Opportunities for Therapeutic Modulation of O-GlcNAc Christina Woo · Chemical Reviews 50 2024 Photo-affinity and metabolic labeling probes based on the opioid alkaloids Christina Woo · ChemBioChem 7 2024 Photoaffinity labelling with small molecules Christina Woo · Nature Reviews Methods Primers 40 2024 Protocol for the comprehensive biochemical and cellular profiling of small-molecule degraders using CoraFluor TR-FRET technology Christina Woo · STAR Protocols 7 2024 Sanglifehrin A mitigates multi-organ fibrosis by targeting the collagen chaperone cyclophilin B Christina Woo · JCI Insight 11 2024 Small molecules help misplaced proteins hitchhike around cells Christina Woo · Nature 0 2024 The Cyclimids: Degron-inspired cereblon binders for targeted protein degradation Christina Woo · Cell Chemical Biology 51 2024 Ubiquitin gets sweet: Sugar-mediated ubiquitination regulates Nrf1 function Christina Woo · Molecular Cell 0 2023 A versatile isocyanate-mediated strategy for appending chemical tags onto drug-like small molecules Christina Woo · Bioconjugate Chemistry 2 2023 Chemical tools for the opioids Christina Woo · Molecular and Cellular Neuroscience 4 2023 Design and development of IKZF2 and CK1a dual degraders Christina Woo · Journal of Medicinal Chemistry 25 2023 Dual IKZF2 and CK1a degrader targets acute myeloid leukemia cells Christina Woo · Cancer Cell 51 2023 Dual-specificity RNA aptamers: A sweet new tool for studying O-GlcNAc biology Christina Woo · Molecular Cell 1 2023 Photoaffinity labeling chemistries used to map biomolecular interactions Christina Woo · Israel Journal of Chemistry 36 2023 Small molecule-activated O-GlcNAcase for spatiotemporal removal of O-GlcNAc in live cells Christina Woo · ACS Chemical Biology 14 2022 4-Deoxy-4-fluoro-GalNAz (4FGalNAz) Is a Metabolic Chemical Reporter of O-GlcNAc Modifications, Highlighting the Notable Substrate Flexibility of O-GlcNAc Transferase Christina Woo · ACS Chemical Biology 18 2022 A chemoproteomics approach to profile phospholipase D-derived phosphatidyl alcohol interactions Christina Woo · ACS Chemical Biology 27 2022 A general approach to identify miniature cell-permeable and synthetic anti-CRISPRs Christina Woo · Nat Cell Biol · needs review — 2022 Design and evaluation of a cyclobutane diazirine alkyne tag for photoaffinity labeling in cells Christina Woo · Journal of the American Chemical Society 42 2022 Development of photo-lenalidomide for cellular target identification Christina Woo · Journal of the American Chemical Society 44 2022 Methods to characterize and discover molecular degraders in cells Christina Woo · Chemical Society Reviews 6 2022 Molecular and structural characterization of lenalidomide-mediated sequestration of eIF3i Christina Woo · ACS Chemical Biology 5 2022 The E3 ubiquitin ligase adaptor cereblon targets the C-terminal cyclic imide degron Christina Woo · Nature 194 2022 The schizophrenia-associated variant in SLC39A8 alters N-glycosylation in the mouse brain Christina Woo · Molecular Psychiatry 53 2022 Writing and erasing O-GlcNAc on casein kinase 2 alpha alters the phosphoproteome Christina Woo · ACS Chemical Biology 22 2021 Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies of glycopeptide data Christina Woo · Nature Methods 162 2021 E3 ligase binders and uses thereof Christina Woo · Patent Application 63/174,389 — 2021 Enantioselective synthesis and biological evaluation of sanglifehrin A and B and analogs Christina Woo · Angewandte Chemie International Edition 22 2021 Immunomodulatory compounds and uses thereof Christina Woo · Patent Application 63/018122 — 2021 Ironing out new antibiotic mechanisms with xanthocillin X Christina Woo · ACS Central Science 6 2021 Labeling preferences of diazirines with protein biomolecules Christina Woo · Journal of the American Chemical Society 218 2021 Nanobody-OGA fusions and uses thereof Christina Woo · Patent Application 63/158,244 — 2021 O-GlcNAc engineering on a target protein in cells with nanobody-OGT and nanobody-splitOGA Christina Woo · Current Protocols 18 2021 Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase Christina Woo · Nature Chemical Biology 110 2021 The crossroads of glycoscience, infection, and immunology Christina Woo · Frontiers in Microbiology 7 2021 Truncation of the TPR domain of OGT alters substrate and glycosite selection Christina Woo · Analytical and Bioanalytical Chemistry 33 2021 Writing and erasing O-GlcNAc from target proteins in cells Christina Woo · Biochemical Society Transactions —