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2026 From Alchemy to Precision Skeletal Editing Jimmy Wu · Science 2025 Selectivity Rules for the Dearomative (3+2) Annulation Reaction Between Substituted Indoles and Oxyallyl Cations Jimmy Wu · Advanced Synthesis & Catalysis 1 2025 Synthesis of Indolyl-7-azanorbornanes by Decomposition of Tetrahydro-1,2,3-triazepines Jimmy Wu · Advanced Synthesis & Catalysis 0 2024 Synthesis of Functionalized Hexahydrocarbazoles by Beckmann Elimination and Nucleophile-Intercepted Beckmann Fragmentation Jimmy Wu · Organic Letters 6 2023 Regiodivergent (3+2) Annulation Reactions of Oxyallyl Cations Jimmy Wu · Chemical Science 16 2021 Cycloalkanyl[b]indoles Useful as GLP-1 Modulators Jimmy Wu · EP 2887804 B1 2020 Diversification of Nucleophile-Intercepted Beckmann Fragmentation (NuBFr) Products and Related DFT Studies Jimmy Wu · The Journal of Organic Chemistry 9 2020 Method for Synthesizing Cycloalkanyl[b]indoles, Cycloakanyl[b]benzo-furans, Cycloalkanyl[b]benzothiophenes, Compounds and Methods of Use Jimmy Wu · JP 6653573 B2 2019 Nucleophile-Intercepted Beckmann Fragmentation Reactions Jimmy Wu · Chemical Science 26 2019 Nuphar Alkaloids Induce Very Rapid Apoptosis Through a Novel Caspase-Dependent but BAX/BAK-Independent Pathway Jimmy Wu · Cell Biology and Toxicology 7 2018 Canvass: A Crowd-Sourced, Natural-Product Screening Library for Exploring Biological Space Jimmy Wu · ACS Central Science 43 2018 Catalytic Vinylogous Cross-Coupling Reactions of Rhenium Vinylcarbenoids Jimmy Wu · Chemical Science 15 2018 Methods of Inhibiting PCSK9 Jimmy Wu · PCT WO2018129205A1 2018 Synthesis of 2-Aminoimidazolones and Imidazolones by (3+2) Annulation of Azaoxyallyl Cations Jimmy Wu · Organic Letters 75 2017 Antibiotic Compositions Jimmy Wu · PCT WO2017136642A1 2017 A Quinolinol-Based Small Molecule with Anti-MRSA Activity that Targets Bacterial Membrane and Promotes Fermentative Metabolism Jimmy Wu · The Journal of Antibiotics 8 2017 Method for Synthesizing Cycloalkanyl[b]indoles, Cycloalkanyl[b]benzofurans, Cycloalkanyl[b]benzothiophenes, Compounds and Methods of Use Jimmy Wu · US 9,598,365 B2 2017 Stereoselective Synthesis and Biological Evaluation of C1-Epimeric and Desmethyl Monomeric Nuphar Analogues Jimmy Wu · The Journal of Organic Chemistry 13 2017 Transition Metal-Free C3 Arylation of Indoles with Aryl Halides Jimmy Wu · Angewandte Chemie International Edition 85 2016 Enantioselective Formal Syntheses of 11 Nuphar Alkaloids and Discovery of Potent Apoptotic Monomeric Analogues Jimmy Wu · Angewandte Chemie International Edition · needs review 16 2016 Synthetic Small Molecule GLP-1 Secretagogues Prepared by Means of a Three-Component Indole Annulation Strategy Jimmy Wu · Scientific Reports 20 2015 (3+2)-Cycloaddition Reactions of Oxyallyl Cations Jimmy Wu · Synthesis · needs review 57 2015 Dearomative Indole (3+2) Reactions with Azaoxyallyl Cations – New Method for the Synthesis of Pyrroloindolines Jimmy Wu · Journal of the American Chemical Society 186 2015 Total Syntheses and Biological Evaluation of Both Enantiomers of Several Hydroxylated Dimeric Nuphar Alkaloids Jimmy Wu · Angewandte Chemie International Edition 25 2015 Vinylogous Mukaiyama–Michael Reactions of Dihydropyridinones Jimmy Wu · Organic Letters 15 2014 Dearomative Indole (3+2) Cycloaddition Reactions Jimmy Wu · Journal of the American Chemical Society · needs review 161 2014 Diethylphosphorothioic Acid Jimmy Wu · Encyclopedia of Reagents for Organic Synthesis 0 2014 Hydrothiolation of Unactivated Alkenes Jimmy Wu · US 8,816,094 B2 2014 Regioselective Formal Hydroamination of Styrenes with 1-Phenyl-1H-tetrazole-5-thiol Jimmy Wu · ChemInform · needs review 0 2014 Review of Recent Advances in Nucleophilic C–F Bond-forming Reactions Jimmy Wu · Tetrahedron Letters · needs review 101 2013 Markovnikov-Selective Hydrothiolation of Styrenes: Application to the Synthesis of Stereodefined Trisubstituted Olefins Jimmy Wu · Organic Letters · needs review 48 2013 Redox Chain Reaction — Indole and Pyrrole Alkylation with Unactivated 2° Alcohols Jimmy Wu · Angewandte Chemie International Edition · needs review 69 2012 Ga(III)-Catalyzed Three-Component (4+3) Cycloaddition Reactions Jimmy Wu · Angewandte Chemie International Edition 124 2012 Pd-Catalyzed Allylic Fluorination of Cinnamyl Phosphorothioate Esters Jimmy Wu · Organic Letters 95 2012 Phosphorothioic Acids and Related Compounds as Surrogates for H2S – Synthesis of Chiral Tetrahydrothiophenes Jimmy Wu · Journal of the American Chemical Society · needs review 65 2011 Cu(I)-Catalyzed, -Selective, Allylic Alkylation Reactions between Phosphorothioate Esters and Organomagnesium Reagents Jimmy Wu · Journal of the American Chemical Society · needs review 113 2011 Direct Annulation and Alkylation of Indoles with 2-Aminobenzyl Alcohols Catalyzed by TFA Jimmy Wu · Tetrahedron · needs review 60 2010 Convenient Synthesis of Allylic Thioethers from Phosphorothioate Esters and Alcohols Jimmy Wu · Organic Letters · needs review 46 2010 Ga(OTf)3-Catalyzed Direct Substitution of Alcohols with Sulfur Nucleophiles Jimmy Wu · Organic Letters 95 2010 Mild Two-Step Process for the Transition Metal-Free Synthesis of Carbon−Carbon Bonds from Allylic Alcohols/Ethers and Grignard Reagents Jimmy Wu · Journal of the American Chemical Society · needs review 68 2006 Asymmetric, anti-Selective Scandium-Catalyzed Sakurai Additions to Glyoxamide. Applications to the Syntheses of N-Boc d-Alloisoleucine and d-Isoleucine Jimmy Wu · ChemInform 0 2006 Stereoselective Preparation of a Cyclopentane-Based NK1 Receptor Antagonist Bearing an Unsymmetrically Substituted Sec-Sec Ether Jimmy Wu · The Journal of Organic Chemistry 17 2005 Enantioselective Syn-Selective Scandium-Catalyzed Ene Reactions Jimmy Wu · Journal of the American Chemical Society 104 2003 Enantioselective Indole Friedel−Crafts Alkylations Catalyzed by Bis(oxazolinyl)pyridine-Scandium(III) Triflate Complexes Jimmy Wu · Journal of the American Chemical Society 219 2003 Enantioselective Rare-Earth Catalyzed Quinone Diels−Alder Reactions Jimmy Wu · Journal of the American Chemical Society 92 2003 Unfunctionalized, -Epimerizable Nonracemic Ketones and Aldehydes Can Be Accessed by Crystallization-Induced Dynamic Resolution of Imines Jimmy Wu · Journal of the American Chemical Society 48 2002 A General Method for the Enantioselective Synthesis of Pantolactone Derivatives Jimmy Wu · Organic Letters 69 2002 Asymmetric Synthesis of 1,2,3-Trisubstituted Cyclopentanes and Cyclohexanes as Key Components of Substance P Antagonists Jimmy Wu · The Journal of Organic Chemistry 38 2002 C2-Symmetric Sc(III)–Complexes as Chiral Lewis Acids. Catalytic Enantioselective Aldol Additions to Glyoxylate Esters Jimmy Wu · Organic Letters · needs review 79 2001 A General Preparation of Pyridines and Pyridones Via the Annulation of Ketones and Esters Jimmy Wu · The Journal of Organic Chemistry · needs review 55
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2026 · review · journal

From Alchemy to Precision Skeletal Editing

Science · Jimmy Wu

in CV
noneScholar citations
noneOpenAlex citations

From the CV

lines 166–166 · published

31. “From Alchemy to Precision Skeletal Editing” Wu, J. Science, 2026, 392, 470.

Peer reviewed
yes
First author
Wu
Co-authors
none
Subfield
other
Method
review
Invited
none
Publisher
none
Reprint or translation
none
DOI
10.1126/science.aeh2468

Where each field came from

FieldCVOpenAlexScholar
title From Alchemy to Precision Skeletal Editing (used)
year 2026 (used)
venue Science (used)
kind review (used)
DOI 10.1126/science.aeh2468 (used)
first author Wu (used)

The value in bold is the one the record uses.

How the records were joined

No decision recorded; a single record.