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Journal
Nature Chemical Biology
Citation weight
TierB
Weight in force1×
Weightingoff
Weight inputs
Each figure with its percentile among the ranked journals. A is the median, over the academics with a work here, of that academic’s citations to the works this site counts for them - never a Google Scholar profile total. Over every academic of this field, all years, whatever the filters select.
A · academics’ median13,139.5 · 58%
B · citations per work244.8 · 85%
N · works101 · 73%
P · academics24 · 66%
Formula result1.075
From this institution
Under these filters. A work with no citation count is unknown here, never a zero.
Works99
Citations21,290 over 86 of 99 works
Citations per counted work247.6
Weighted citations—
Academics24
Departments6
First seen2005
Works placed per year
99 of these 99 works carry a year; an undated work is in no year. Works placed, under these filters.
Departments publishing there 6
| Department | Works |
|---|---|
| Harvard Chemistry | 33 |
| Princeton Chemistry | 33 |
| Penn Chemistry | 18 |
| Yale Chemistry | 9 |
| Cornell Chemistry | 6 |
| Columbia Chemistry | 3 |
A work held by two departments counts once in each, so these add up to more than the works above.
Works placed there 99
| Year | Title | Academics | Citations |
|---|---|---|---|
| 2009 | Absolute metabolite concentrations and implied enzyme active site occupancy in Escherichia coli | Joshua Rabinowitz | 2,317 |
| 2011 | Chemistry and biology of reactive oxygen species in signaling or stress responses | Christopher J. Chang | 2,200 |
| 2008 | Synthetic fluorescent sensors for studying the cell biology of metals | Christopher J. Chang | 1,262 |
| 2018 | How many human proteoforms are there? | Sarah Slavoff · Tom Muir | 1,201 |
| 2015 | Minimum information about a biosynthetic gene cluster. | Emily Balskus | 922 |
| 2013 | Peptidomic discovery of short open reading frame–encoded peptides in human cells | Sarah Slavoff | 820 |
| 2006 | Allosteric Control of an Ionotropic Glutamate Receptor with an Optical Switch | Dirk Trauner | 736 |
| 2016 | Histone deacetylase 6 structure and molecular basis of catalysis and inhibition | David W. Christianson | 606 |
| 2015 | Small Molecule-Triggered Cas9 Protein with Improved Genome-Editing Specificity | David R. Liu | 560 |
| 2011 | H2B Ubiquitylation Disrupts Local and Higher-Order Chromatin Compaction | Tom Muir | 548 |
| 2016 | Metabolite concentrations, fluxes and free energies imply efficient enzyme usage | Joshua Rabinowitz | 548 |
| 2007 | Molecular imaging of hydrogen peroxide produced for cell signaling | Christopher J. Chang | 531 |
| 2007 | Small-molecule pheromones that control dauer development in Caenorhabditis elegans | Frank C. Schroeder | 475 |
| 2020 | Targeted desialylation overcomes glyco-immune checkpoints and potentiates the anticancer immune response in vivo | Stacy Malaker | 426 |
| 2006 | How Pathogenic Bacteria Evade Mammalian Sabotage in the Battle for Iron | David R. Liu | 412 |
| 2020 | m6A-binding YTHDF proteins promote stress granule formation | Xiaowei Zhuang | 392 |
| 2017 | A human microprotein that interacts with the mRNA decapping complex | Sarah Slavoff | 372 |
| 2017 | Continuous Directed Evolution of Aminoacyl-tRNA Synthetases | David R. Liu | 357 |
| 2011 | Nox2 redox signaling maintains essential cell populations in the brain | Christopher J. Chang | 352 |
| 2011 | α-Ketoglutarate coordinates carbon and nitrogen utilization via enzyme I inhibition | Joshua Rabinowitz | 299 |
| 2010 | Disulfide-directed histone ubiquitylation reveals plasticity in hDot1L activation | Tom Muir | 289 |
| 2016 | Copper regulates cyclic-AMP-dependent lipolysis | Christopher J. Chang | 261 |
| 2015 | Searching for harmony in transition-metal signaling | Christopher J. Chang | 234 |
| 2020 | A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway | Joshua Rabinowitz | 234 |
| 2011 | Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthase | David W. Christianson | 218 |
| 2008 | Reconstitution of ThiC in thiamine pyrimidine biosynthesis expands the radical SAM superfamily | Squire J. Booker | 200 |
| 2014 | Direct nitration and azidation of aliphatic carbons by an iron-dependent halogenase. | Megan L. Matthews | 192 |
| 2023 | Functional spectrum and specificity of mitochondrial ferredoxins FDX1 and FDX2 | Squire J. Booker | 185 |
| 2018 | Copper regulates rest-activity cycles through the locus coeruleus-norepinephrine system | Christopher J. Chang | 184 |
| 2013 | Direct Detection of Protein Histidine Phosphorylation Using a Pan Antibody | Tom Muir | 179 |
| 2012 | Chromatin as an Expansive Canvas for Chemical Biology | Tom Muir | 166 |
| 2016 | Photoswitchable Diacylglycerols Enable Optical Control of Protein Kinase C | Dirk Trauner | 165 |
| 2005 | Photochemical Tools for Remote-Control of Ion Channels in Excitable Cells | Dirk Trauner | 161 |
| 2016 | A two-step activation mechanism controls the histone methyltransferase Suv39h1 | Tom Muir | 159 |
| 2021 | A community resource for paired genomic and metabolomic data mining | Jason M. Crawford | 151 |
| 2007 | Post-translational Enzyme Activation in an Animal Via Conditional Protein Splicing | Tom Muir | 126 |
| 2019 | CRISPR-suppressor scanning reveals a nonenzymatic role of LSD1 in AML | Brian Liau | 123 |
| 2021 | Oncohistone mutations enhance chromatin remodeling and alter cell fate | Tom Muir | 113 |
| 2014 | Design of activated serine-containing catalytic triads with atomic-level accuracy. | Megan L. Matthews | 111 |
| 2021 | Target protein deglycosylation in living cells by a nanobody-fused split O-GlcNAcase | Christina Woo | 110 |
| 2015 | Chemical Proteomics Reveals a γH2AX-53BP1 Interaction in the DNA Damage Response | Ralph Kleiner | 110 |
| 2017 | Optogenetic control of kinetochore function | David M. Chenoweth | 108 |
| 2017 | Ubiquitin Utilizes an Acidic Surface Patch to Alter Chromatin Structure | Tom Muir | 108 |
| 2017 | A new strategy for aromatic ring alkylation in cylindrocyclophane biosynthesis. | Emily Balskus | 107 |
| 2016 | Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus | Frank C. Schroeder | 106 |
| 2017 | Bisphosphoglycerate mutase controls 3-phosphoglycerate concentration and thereby serine pathway flux | Tom Muir | 103 |
| 2018 | Acetylation blocks DNA damage-induced chromatin ADP-ribosylation | Tom Muir | 102 |
| 2019 | Optical Control of Sphingosine-1-Phosphate Formation and Function | Dirk Trauner | 96 |
| 2020 | A basic motif anchoring ISWI to the nucleosome acidic patch regulates nucleosome spacing | Tom Muir | 96 |
| 2020 | Chromatin as a key consumer in the metabolic economy | Tom Muir | 94 |
| 2010 | Branched Intermediate Formation Stimulates Peptide Bond Cleavage in the Mxe GyrA Intein Protein Splicing Reaction | Tom Muir | 92 |
| 2010 | An In Vitro Translation, Selection and Amplification System for Peptide Nucleic Acid | David R. Liu · Ralph Kleiner | 90 |
| 2008 | Biomimetic Synthesis of the IDO Inhibitors Exiguamine A and B | Dirk Trauner | 75 |
| 2021 | Structural basis for non-radical catalysis by TsrM, a radical SAM methylase | Squire J. Booker | 74 |
| 2018 | Optical Control of L-Type Ca2+ Channels Using a Diltiazem Photoswitch | Dirk Trauner | 69 |
| 2019 | An excreted small molecule promotes C. elegans reproductive development and aging | Frank C. Schroeder | 65 |
| 2017 | Colibactin assembly line enzymes use S-adenosylmethionine to build a cyclopropane ring. | Emily Balskus | 64 |
| 2018 | A De Novo Enzyme Catalyzes a Life-Sustaining Reaction in E. coli | Michael Hecht | 64 |
| 2023 | Base editor scanning charts the DNMT3A activity landscape | Brian Liau | 63 |
| 2013 | A substrate radical intermediate in catalysis by the antibiotic resistance protein Cfr | Squire J. Booker | 63 |
| 2012 | Highly specific, bisubstrate-competitive Src inhibitors from DNA-templated macrocycles | David R. Liu · Ralph Kleiner | 62 |
| 2021 | Activity-based RNA-modifying enzyme probing reveals DUS3L-mediated dihydrouridylation | Ralph Kleiner | 61 |
| 2013 | Induction of innate and adaptive immunity in vivo by delivery of poly dA:dT to dendritic cells | Tom Muir | 56 |
| 2023 | A small molecule inhibitor prevents gut bacterial genotoxin production. | Emily Balskus | 54 |
| 2017 | GlcN6P cofactor serves multiple catalytic roles in the glmS ribozyme | Sharon Hammes-Schiffer | 54 |
| 2009 | Natural Amino Acids Do Not Require Their Native tRNAs for Efficient Selection by the Ribosome | Ruben L Gonzalez Jr · Virginia W. Cornish | 52 |
| 2021 | Escherichia coli small molecule metabolism at the host–microorganism interface | Jason M. Crawford | 46 |
| 2022 | Nascent alt-protein chemoproteomics reveals a pre-60S assembly checkpoint inhibitor | Sarah Slavoff | 43 |
| 2021 | Discovering new biology with drug-resistance alleles | Brian Liau | 31 |
| 2023 | Structural basis of colibactin activation by the ClbP peptidase. | Emily Balskus | 30 |
| 2023 | Profiling dynamic RNA-protein interactions using small molecule-induced RNA editing | Ralph Kleiner | 30 |
| 2010 | Synthetic Immunology to Engineer Human Immunity | David Spiegel | 28 |
| 2023 | Drug addiction unveils a repressive methylation ceiling in EZH2-mutant lymphoma | Brian Liau | 23 |
| 2025 | Uncoupling histone modification crosstalk by engineering lysine demethylase LSD1 | Brian Liau | 19 |
| 2020 | Multiplexed genomic encoding of non-canonical amino acids for labeling large complexes | Ruben L Gonzalez Jr | 14 |
| 2025 | PCMT1 generates the C-terminal cyclic imide degron on CRBN substrates | Christina Woo | 12 |
| 2014 | Sponge symbionts play defense. | Emily Balskus | 7 |
| 2026 | Membrane editing with proximity labeling reveals regulators of lipid homeostasis | Jeremy M. Baskin | 5 |
| 2021 | There is a lock for every key: MEMBRANE PROTEINS | Jeremy M. Baskin | 4 |
| 2025 | All roads lead to OSBP: Lipid metabolism | Jeremy M. Baskin | 4 |
| 2026 | Xylosyltransferase engineering to manipulate proteoglycans in mammalian cells | Stacy Malaker | 3 |
| 2008 | Navigating the RNA folding landscape | Ruben L Gonzalez Jr | 2 |
| 2021 | Voices of chemical biology | Megan L. Matthews | 2 |
| 2025 | Building the first base editors: Genome editing | Brian Liau | 1 |
| 2020 | Rolf Huisgen (1920–2020) | Dirk Trauner | 1 |
| 2005 | A Glimpse at the Grail | Dirk Trauner | 0 |
| 2012 | Discovery and Biological Characterization of Geranylated RNA in Bacteria | David R. Liu | — |
| 2019 | Side-Chain Determinants of Biopolymer Function During Iterated Selection and Replication | David R. Liu | — |
| 2014 | Electrophilic Activity-Based RNA Probes Reveal a Self-Alkylating RNA for RNA Labeling | David R. Liu | — |
| 2017 | Crystal Structures Reveal an Elusive Functional Domain of Pyrrolysyl-tRNA Synthetase | David R. Liu | — |
| 2009 | LC/MS Analysis of Cellular RNA Reveals NAD-Linked RNA | David R. Liu | — |
| 2019 | Substrate-Selective Inhibitors that Reprogram the Activity of Insulin-Degrading Enzyme | David R. Liu | — |
| 2023 | Assigning Functionality to Cysteines by Base Editing of Cancer Dependency Genes | David R. Liu | — |
| 2014 | Negative Selection And Stringency Modulation Enable Phage-Assisted Continuous Evolution (PACE) of Enzymes with Altered Specificity | David R. Liu | — |
| 2021 | Laboratory Evolution of a Sortase Enzyme that Modifies Amyloid-β Protein | David R. Liu | — |
| 2022 | Discovery and Molecular Basis of Subtype-Selective Cyclophilin Inhibitors | David R. Liu | — |
| 2020 | The Developing Toolkit of Continuous Directed Evolution | David R. Liu | — |
| 2021 | Reconstruction of Evolving Gene Variants and Fitness from Short Sequencing Reads | David R. Liu | — |
| 2018 | Continuous Directed Evolution of Proteins with Improved Soluble Expression | David R. Liu | — |
Citations as counted, before any journal weight: 86 of these 99 works carry a count, and a work with no count is unknown, never a zero.