Journal

Bioorganic & Medicinal Chemistry Letters

ISSN 0960-894X · Elsevier BV

OpenAlex S30970080

Published here

59 counted works of 59 linked

YearTitleAcademicsSources
2021 Anticancer properties of bisaminoquinolines with modified linkers Jeffrey D. Winkler OA GS
2021 Targeted delivery of mPGES-1 inhibitors to macrophages via the folate receptor-β for inflammatory pain Jeffrey D. Winkler OA GS
2020 Structure and bioactivity of colibactin Jason M. Crawford GS
2020 Targeting the TS dimer interface in bifunctional Cryptosporidium hominis TS-DHFR from parasitic protozoa: Virtual screening identifies novel TS allosteric inhibitors. William Jorgensen CV OA
2019 Analysis of chain length, substitution patterns, and unsaturation of AM-404 derivatives as 20S proteasome stimulators Timothy Newhouse CV OA GS
2019 Molecular and Cellular Studies Evaluating a Potent 2-Cyanoindolizine Catechol Diether NNRTI Targeting Wildtype and Y181C Mutant HIV-1 Reverse Transcriptase William Jorgensen CV OA
2019 Novel Allosteric Covalent Inhibitors of Bifunctional Cryptosporidium hominis TS- DHFR from Parasitic Protozoa Identified by Virtual Screening. William Jorgensen CV OA
2016 Irregularities in enzyme assays: the case of macrophage migration inhibitory factor William Jorgensen CV OA
2016 PUMA-Dependent Apoptosis in NSCLC Cancer Cells by a Dimeric β-Carboline Jeffrey D. Winkler CV OA GS
2015 A nanotherapy strategy significantly enhances anticryptosporidial activity of an inhibitor of bifunctional thymidylate synthase-dihydrofolate reductase from Cryptosporidium William Jorgensen CV OA
2015 A selective phosphine-based fluorescent probe for nitroxyl in living cells Ming Xian GS
2015 Discovery and crystallography of bicyclic arylaminoazines as potent inhibitors of HIV-1 reverse transcriptase William Jorgensen CV OA
2015 Synthesis of Benzopentathiepin Analogs and Their Evaluation as Inhibitors of the Phosphatase STEP Jon Ellman CV OA
2015 Tetrafluorophenoxymethyl Ketone Cruzain Inhibitors with Improved Pharmacokinetic Properties as Therapeutic Leads for Chagas’ Disease Jon Ellman CV OA GS
2014 Structural studies provide clues for analog design of specific inhibitors of Cryptosporidium hominis thymidylate synthase-dihydrofolate reductase William Jorgensen CV OA
2014 Virtual screening reveals allosteric inhibitors of the Toxoplasma gondii thymidylate synthase-dihydrofolate reductase William Jorgensen CV OA
2013 Arnold, E.; Anderson, K. S.; Jorgensen, W. L. William Jorgensen CV
2013 Extension into the entrance channel of HIV-1 reverse transcriptase—Crystallography and enhanced solubility William Jorgensen CV OA
2013 Optimization of benzyloxazoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase to enhance Y181C potency. William Jorgensen CV OA
2013 Optimization of diarylazines as anti-HIV agents with dramatically enhanced solubility William Jorgensen CV OA
2012 Crystal Structures of AKR1C3 Containing an N-(Aryl)amino-benzoate Inhibitor and a Bifunctional AKR1C3 Inhibitor and Androgen Receptor Antagonist. Therapeutic Leads for Castrate Resistant Prostate Cancer Jeffrey D. Winkler CV OA GS
2012 Discovery of dimeric inhibitors by extension into the entrance channel of HIV-1 reverse transcriptase. William Jorgensen CV OA
2011 Benzisothiazolones as modulators of macrophage migration inhibitory factor. William Jorgensen CV OA
2011 Discovery of Substituted 3-(Phenylamino)benzoic acids as Potent and Selective Inhibitors of Type 5 17β-Hydroxysteroid Dehydrogenase (AKR1C3) Jeffrey D. Winkler CV OA GS
2011 Pancreatic anticancer activity of a novel geranylgeranylated coumarin derivative Christina Woo CV OA
2010 Eastern extension of azoles as non-nucleoside inhibitors of HIV-1 reverse transcriptase; cyano group alternatives. William Jorgensen CV OA
2010 Optimization of N-benzyl-benzoxazol-2-ones as receptor antagonists of macrophage migration inhibitory factor (MIF). William Jorgensen CV OA GS
2010 Receptor agonists of macrophage migration inhibitory factor. William Jorgensen CV OA
2009 Fragment-based discovery of selective inhibitors of the Mycobacterium tuberculosis protein tyrosine phosphatase PtpA Jon Ellman CV OA GS
2009 Novel Non-Active Site Inhibitor of Cryptosporidium hominis TS-DHFR Identified by a Virtual Screen. William Jorgensen CV OA
2009 Vancomycin Resistance: Modeling Backbone Variants with D-Ala-D-Ala and D-Ala-D-Lac Peptides. William Jorgensen CV OA
2008 Energetic effects for observed and unobserved HIV-1 reverse transcriptase mutations of residues L100, V106, and Y181 in the presence of nevirapine and efavirenz. William Jorgensen CV OA
2008 RNA bandages for photomodulating in vitro protein synthesis Ivan J. Dmochowski CV OA GS
2006 Computer-Aided Design of Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. William Jorgensen CV OA GS
2006 Optimization of Diarylamines as Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. William Jorgensen CV OA
2006 Optimization of Pyrimidinyl- and Triazinyl-amines as Non-Nucleoside Inhibitors of HIV-1 Reverse Transcriptase. William Jorgensen CV OA
2005 Glycosidase Inhibition by 1-Glycosyl-4-Phenyl Triazoles Amit Basu CV OA
2005 Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides Ivan J. Dmochowski CV OA GS
2005 Potent 4-Aminopiperidine Based Antimalarial Agents Jon Ellman CV OA
2004 3-Methoxycarbonyl-5-nitrophenyl boronic acid: High affinity diol recognition at neutral pH Amit Basu CV OA
2003 Activity Predictions for Efavirenz Analogues with the K103N Mutant of HIV Reverse Transcriptase. William Jorgensen CV OA
2003 Identification of Potent and Broad-Spectrum Antibiotics from SAR Studies of a Synthetic Vancomycin Analog Jon Ellman CV OA GS
2003 Structure Activity Studies of a Novel Cytotoxic Benzodiazepine Jon Ellman CV OA GS
2002 Design and Synthesis of Novel Inhibitors of Gelatinase B Jon Ellman CV OA GS
2002 Electrochemical and peroxidase oxidation study of N′-Hydroxyguanidine derivatives as NO donors Ming Xian GS
2002 Estimation of Binding Affinities for Celecoxib Analogues with COX-2 via Monte Carlo – Extended Linear Response. William Jorgensen CV OA
2002 General Solid-Phase Procedure to Prepare Novel Cyclic Ketone Inhibitors of the Cysteine Protease Cruzain Jon Ellman CV OA
2002 Tyrosylprotein Sulfotransferase Inhibitors Generated by Combinatorial Target-Guided ligand Assembly Jon Ellman CV OA GS
2001 Antiviral Drug Design: Computational Analyses of the Effects of the L100I Mutation for HIV-RT on the Binding of NNRTIs. William Jorgensen CV OA
2001 Equilibrium and kinetics studies of transnitrosation between S-nitrosothiols and thiols Ming Xian GS
2001 Fluorescent Monitoring of Kinase Activity in Real Time: Development of a Robust Fluorescence-based Assay for Abl Tyrosine Kinase Activity Tom Muir CV OA GS
2001 Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents Bruce Ganem GS
2001 Rationale for the Observed COX-2/COX-1 Selectivity of Celecoxib from Monte Carlo Simulations William Jorgensen CV OA
2000 Computational Binding Studies of Human pp60c-src SH2 Domain with a Series of Nonpeptide, Phosphophenyl-Containing Ligands William Jorgensen CV OA
2000 Optimization of a Somatostatin Mimetic via Constrained amino acid and Backbone Incorporation Jon Ellman CV OA
2000 Prediction of Drug Solubility from Monte Carlo Simulations William Jorgensen CV OA GS
1998 Novel Inhibitors of 41 Integrin Receptor Interactions Through Library Synthesis and Screening Jon Ellman CV OA GS
1996 A Model for the Taxol/Epothilone Pharmacophore Jeffrey D. Winkler CV OA GS
1993 Synthesis of Ingenol Analogs with Affinity for Protein Kinase C Jeffrey D. Winkler CV OA GS