Journal

ACS Medicinal Chemistry Letters

Published here

17 counted works of 17 linked

YearTitleAcademicsSources
2021 Covalent Inhibition of Wild-Type HIV-1 Reverse Transcriptase Using a Fluorosulfate Warhead. William Jorgensen CV OA
2021 Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency. William Jorgensen CV OA
2020 Discovery of a cyclic choline analog that inhibits anaerobic choline metabolism by human gut bacteria. Emily Balskus CV OA
2020 Identification of 14 Known Drugs as Inhibitors of the Main Protease of SARS-CoV-2. William Jorgensen CV OA GS
2020 Structure-Guided Identification of DNMT3B Inhibitors. William Jorgensen CV OA
2018 Design, Synthesis and Biological Evaluation of Allosteric Effectors that Enhance CO Release from Carboxyhemoglobin Jeffrey D. Winkler CV OA GS
2018 Synthesis and Biological Evaluation of an Indazole-Based Selective Protein Arginine Deiminase 4 (PAD4) Inhibitor Jon Ellman CV OA
2018 Synthesis and Structure-Activity Relationship Study of Biliatresone, a Plant Isoflavonoid That Causes Biliary Atresia Jeffrey D. Winkler CV OA GS
2017 Adding a Hydrogen Bond May Not Help: Naphthyridinone vs. Quinoline Inhibitors of Macrophage Migration Inhibitory Factor. William Jorgensen CV OA
2017 Identification and Characterization of Small Molecules Binding to the JAK2 Pseudokinase Domain. William Jorgensen CV OA
2017 JAK2-JH2 Fluorescence Polarization Assay and Crystal Structures for Complexes with Three Small Molecules. William Jorgensen CV OA
2017 Systematic Study of Effects of Structural Modifications on the Aqueous Solubilities of Drug-like Molecules. William Jorgensen CV OA
2016 Cellular Activity of New Small Molecule Protein Arginine Deiminase 3 (PAD3) Inhibitors Jon Ellman CV OA
2016 Design, Conformation, and Crystallography of 2-Naphthyl Phenyl Ethers as Potent Anti-HIV Agents William Jorgensen CV OA
2016 Lee, W.-G.; Chan, A. H.; Spasov, K.A.; Anderson, K. A.; Jorgensen, W. L. William Jorgensen CV
2015 Potent Inhibitors Active Against HIV Reverse Transcriptase with K101P, a Mutation Conferring Rilpivirine Resistance William Jorgensen CV OA
2014 Picomolar Inhibitors of HIV-1 Reverse Transcriptase: Design and Crystallography of Naphthyl Phenyl Ethers William Jorgensen CV OA