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Academic

Dirk Trauner

Academic

RankDistinguished

As of2022 · CV

DepartmentPenn Chemistry

UniversityPenn

FieldChemistry

ORCID0000-0002-6782-6056

Scholarprofile

Totals

Publications372

Citations31,033

h-index90 · Scholar

Citations per year in post1,193.6

Years in post26 from the CV positions

Coverage

Works with a count367 of 372

Share99%

Positions

Penn Integrates Knowledge Professor, Universi…2022–

Janice Cutler Chair in Chemistry, New York Un…2017–2022

Adjunct Professor, NYU Grossman School of Med…2017–2022

Professor of Chemical Biology and Chemical Ge…2008–2017

Associate Professor (with tenure), Department…2006–2010

Member, Lawrence Berkeley National Laboratory2005–2008

Assistant Professor, Department of Chemistry,…2000–2006

Postdoctoral Research Fellow, Sloan-Kettering…1998–2000

and 3 more

Top venues 105 venues

The 8 holding the most of these works; 97 more hold at least one.

Angewandte Chemie International Edition54

Journal of the American Chemical Society48

Organic Letters35

Nature Communications12

The Journal of Organic Chemistry10

ACS Chemical Neuroscience9

Chemistry - A European Journal9

Nature Chemical Biology8

Publications per year

Works this academic published in each year, by the year each work appeared; an undated work is in no year, and a work two colleagues wrote counts for each of them. The kind, works and year filters decide which works are here at all.

Citations per year

Citations received in each year, from this academic’s verified Scholar profile, which counts every citation to everything they ever wrote: no publication filter reaches this line - not the kinds, not the works switch, not the year window on publication - and no journal weight either. It is a profile total, so it does not match the works listed below.

Publications 372 works

Every work these filters select, most cited first and the works with no count at the end: a work nobody has a figure for is unknown, never a zero to be ranked among the works that have one, and it prints an em dash. Each figure is that work’s own citations - Scholar’s count where there is one, else OpenAlex’s - and is not weighted.

Year	Title	Venue	Kind	Citations
2001	The B-Alkyl Suzuki-Miyaura Cross-Coupling Reaction: Development, Mechanistic Study and Applications in Natural Product Synthesis	Angewandte Chemie International Edition	article	1,150
2018	In Vivo Photopharmacology	Chemical Reviews	article	1,068
2004	Light-Activated Ion Channels for Remote Control of Neuronal Firing	Nature Neuroscience	article	1,050
2015	A Roadmap to Success in Photopharmacology	Accounts of Chemical Research	article	869
2006	Allosteric Control of an Ionotropic Glutamate Receptor with an Optical Switch	Nature Chemical Biology	article	736
2016	Beta Cell Hubs Dictate Pancreatic Islet Responses to Glucose	Cell Metabolism	article	540
2009	Optogenetic Identification of Behavioral Module in the Vertebrate Spinal Cord	Nature	article	492
2007	Reversible Photomechanical Switching of Individual Engineered Molecules at a Metallic Surface	Physical Review Letters	article	485
2014	Extraction of Photogenerated Electrons and Holes From a Covalent Organic Framework Integrated Heterojunction	Journal of the American Chemical Society	article	481
2015	Photoswitchable Inhibitors of Microtubule Dynamics Optically Control Mitosis and Cell Death	Cell	article	470
2011	Optochemical Genetics	Angewandte Chemie International Edition	article	439
2007	Remote Control of Neuronal Activity With a Light-Gated Glutamate Receptor	Neuron	article	411
2020	PHOTACs Enable Optical Control of Protein Degradation	Science Advances	article	367
2005	Biosynthetic and Biomimetic Electrocyclizations	Chemical Reviews	article	354
2008	Photochemical Control of Endogenous Ion Channels and Cellular Excitability	Nature Methods	article	309
2012	Photochemical Restoration of Visual Responses in Blind Mice	Neuron	article	307
2009	Photochromic Blockers of Voltage-Gated Potassium Channels	Angewandte Chemie International Edition	article	295
2013	A Red-Shifted, Fast-Relaxing Azobenzene Photoswitch for Visible Light Control of an Ionotropic Glutamate Receptor	Journal of the American Chemical Society	article	261
2013	Optical Control of Metabotropic Glutamate Receptors	Nature Neuroscience	article	258
2004	Enantioselective Nazarov Cyclizations Reactions through Catalytic Asymmetric Proton Transfer	Journal of the American Chemical Society	article	248
2014	Restoring Visual Function in Blind Mice With a Photoswitch That Exploits Electrophysiological Remodeling of Retinal Ganglion Cells	Neuron	article	244
2002	Concise Total Synthesis of (–)-Frondosin B Using a Novel Palladium Catalyzed Cyclization	Angewandte Chemie International Edition	article	241
2012	Label-Free Microscale Thermophoresis Discriminates Sites and Affinity of Protein–Ligand Binding	Angewandte Chemie International Edition	article	233
2011	Tuning Photochromic Ion Channel Blockers	ACS Chemical Neuroscience	article	231
2016	Synthetic Approaches Towards Alkaloids Bearing a-Tertiary Amines	Natural Product Reports	article	230
2008	The Chemistry of Marine Furanocembranoids, Pseudopteranes, Gersolanes, and Related Natural Products.	Natural Product Reports	article	230
2007	Mechanisms of Photoswitch Conjugation and Light Activation of an Ionotropic Glutamate Receptor	Proceedings of the National Academy of Sciences	article	226
2012	Rapid Optical Control of Nociception With an Ion-Channel Photoswitch	Nature Methods	article	221
2007	Reversibly Caged Glutamate: A Photochromic Agonist of Ionotropic Glutamate Receptors	Journal of the American Chemical Society	article	221
2001	DieB-Alkyl-Suzuki-Miyaura-Kreuzkupplung: Entwicklung, Untersuchungen zum Mechanismus und Anwendungen in der Naturstoffsynthese	Angewandte Chemie	article	221
2011	LiGluR Restores Visual Responses in Rodent Models of Inherited Blindness	Molecular Therapy	article	218
2009	New Photochemical Tools for Controlling Neuronal Activity	Current Opinion in Neurobiology	article	215
2003	Efficient Nazarov Cyclizations of 2-Alkoxy-1,4-pentadien-ones	Organic Letters	article	205
2020	Computational Design and Synthesis of a Deeply Red-Shifted and Bistable Azobenzene	Journal of the American Chemical Society	article	202
2012	Optical Control of Genetically Engineered Neuronal Nicotinic Acetylcholine Receptors	Nature Chemistry	article	202
2012	Azo-Propofols: Photochromic Potentiators of GABAA Receptors	Angewandte Chemie International Edition	article	187
2015	Photoswitchable Fatty Acids Enable Optical Control of TRPV1	Nature Communications	article	183
2016	Synthesis of Redshifted Azobenzene Photoswitches via Late-Stage Functionalization	Chemistry - A European Journal	article	179
2005	Concise Synthesis of (±)-Rhazinilam Through Direct Coupling	Organic Letters	article	173
2006	Engineering Light-Gated Ion Channels	Biochemistry	article	167
2006	Total Synthesis of (–)-Heptemerone B and (–)-Guanacastepene E	Journal of the American Chemical Society	article	167
2016	Photoswitchable Diacylglycerols Enable Optical Control of Protein Kinase C	Nature Chemical Biology	article	165
2010	A Light-gated, Potassium-selective Glutamate Receptor for the Optical Inhibition of Neuronal Firing	Nature Neuroscience	article	165
1999	Total Synthesis of (+)-Halichlorine, an Inhibitor of VCAM-1 Expression	Angewandte Chemie International Edition	article	162
2005	Photochemical Tools for Remote-Control of Ion Channels in Excitable Cells	Nature Chemical Biology	article	161
2017	Light-Controlled Membrane Mechanics and Shape Transitions of Photoswitchable Lipid Vesicles	Langmuir	article	159
2020	Microtubules control cellular shape and coherence in amoeboid migrating cells	The Journal of Cell Biology	article	157
2000	Morphine Synthesis and Biosynthesis - an Update	Current Organic Chemistry	article	154
2014	A Photochromic Agonist of µ-Opioid Receptors	Angewandte Chemie International Edition	article	153
2006	Exploring Biosynthetic Relationships Among Furanocembranoids: Synthesis of (–)-Bipinnatin J, (+)-Intricarene, (+)-Rubifolide, and (+)-Isoepilophodione B	Organic Letters	article	153
2008	A Structural Link Between Inactivation and Block of a K+ Channel	Nature Structural & Molecular Biology	article	152
2014	Optical Control of Insulin Release Using a Photoswitchable Sulfonylurea	Nature Communications	article	151
2006	Light-Induced Depolarization of Neurons Using a Modified Shaker K Channel and a Molecular Photoswitch	Journal of Neurophysiology	article	149
2015	Orthogonal Optical Control of a G Protein-Coupled Receptor With a SNAP-Tethered Photochromic Ligand	ACS Central Science	article	147
2006	Synthesis of Taiwaniaquinoids Via Nazarov Triflation	Journal of the American Chemical Society	article	145
2008	Ortho-Quinone Methides from para-Quinones: Total Synthesis of Rubioncolin B	Journal of the American Chemical Society	article	143
2012	The V-ATPase-inhibitor Archazolid Abrogates Tumor Metastasis via Inhibition of Endocytic Activation of the Rho-GTPase Rac1	Cancer Research	article	140
2013	Mode of Cell Death Induction by Pharmacological Vacuolar H+-ATPase (V-ATPase) Inhibition	Journal of Biological Chemistry	article	130
2009	Total Synthesis of (±)-Rhazinal Using Novel Palladium-Catalyzed Cyclizations	The Journal of Organic Chemistry	article	130
2005	Biomimetic Synthesis of Antimalarial Naphthoquinones	Journal of the American Chemical Society	article	129
2019	Sign Inversion in Photopharmacology: Incorporation of Cyclic Azobenzenes in Photoswitchable Potassium Channel Blockers and Openers	Angewandte Chemie International Edition	article	126
2017	Synthesis of Photoswitchable Δ9-Tetrahydrocannabinol Derivatives Enables Optical Control of Cannabinoid Receptor 1 Signaling	Journal of the American Chemical Society	article	124
2014	Development of a New Photochromic Ion Channel Blocker via Azologization of Fomocaine	ACS Chemical Neuroscience	article	122
2014	Long Wavelength Optical Control of Glutamate Receptor Ion Channels Using a Tetra-Ortho-Substituted Azobenzene Derivative	Chemical Communications	article	121
2006	Expedient Synthesis of (±)-Bipinnatin J	Organic Letters	article	121
2019	Oxidative Approach Enables Efficient Access to Cyclic Azobenzenes	Journal of the American Chemical Society	article	117
2020	Photoswitchable Lipids	ChemBioChem	article	116
2012	A Photochromic Agonist of AMPA Receptors	Angewandte Chemie International Edition	article	115
2015	Optical Control of Insulin Secretion Using an Incretin Switch	Angewandte Chemie International Edition	article	114
2007	Total Synthesis of (–)-Archazolid B	Journal of the American Chemical Society	article	114
2019	Mapping the Azolog Space Enables the Optical Control of New Biological Targets	ACS Central Science	article	113
2025	Limiting Endosomal Damage Sensing Reduces Inflammation Triggered by Lipid Nanoparticle Endosomal Escape	Nature Nanotechnology	article	109
2014	Optical Control of Acetylcholinesterase with a Tacrine Switch	Angewandte Chemie International Edition	article	109
2010	Structural Basis of Open Channel Block in a Prokaryotic Pentameric Ligand-gated Ion Channel	Nature Structural & Molecular Biology	article	109
2016	Optical Control of Lipid Rafts with Photoswitchable Ceramides	Journal of the American Chemical Society	article	107
2002	Synthetic Studies Toward SNF4435 C and SNF4435 D	Organic Letters	article	105
2017	Restoration of patterned vision with an engineered photoactivatable G protein-coupled receptor	Nature Communications	article	103
2018	Light-Controlled Lipid Interaction and Membrane Organization in Photolipid Bilayer Vesicles	Langmuir	article	102
2015	Optical Control of NMDA-Receptors With a Diffusible Photoswitch	Nature Communications	article	102
2017	Optical Control of Dopamine Receptors Using a Photoswitchable Tethered Inverse Agonist	Journal of the American Chemical Society	article	100
2015	An Eight-Step Synthesis of Epicolactone Reveals its Biosynthetic Origin	Nature Chemistry	article	100
2009	Nanosculpting Reversed Wavelength Sensitivity Into a Photoswitchable iGluR	Proceedings of the National Academy of Sciences	article	99
2017	Dual Optical Control and Mechanistic Insights Into Photoswitchable Group II and III Metabotropic Glutamate Receptors	Proceedings of the National Academy of Sciences	article	97
2005	Biomimetic Synthesis and Structure Elucidation of Rubicordifolin, a Cytotoxic Natural Product from Rubia cordifolia	Journal of the American Chemical Society	article	97
2019	Optical Control of Sphingosine-1-Phosphate Formation and Function	Nature Chemical Biology	article	96
2011	Optogenetic Photochemical Control of Designer K+ Channels in Mammalian Neurons	Journal of Neurophysiology	article	96
2020	Photoswitchable Paclitaxel-Based Microtubule Stabilisers Allow Optical Control Over the Microtubule Cytoskeleton	Nature Communications	article	95
2015	Vacuolar-ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer	Cancer Research	article	93
2007	All Optical Interface for Parallel, Remote, and Spatiotemporal Control of Neuronal Activity	Nano Letters	article	93
2017	Furans as Versatile Synthons: Total Syntheses of Caribenol A and Caribenol B	Journal of the American Chemical Society	article	92
2022	Natural Product Anticipation Through Synthesis	Nature Reviews Chemistry	article	90
2016	A Family of Photoswitchable NMDA Receptors	eLife	article	90
2015	Light-Dark Adaptation of Channelrhodopsin Involves Photoconversion Between the all-trans and 13-cis Retinal Isomers	Biochemistry	article	90
2005	Pericyclic Reactions of Prenylated Naphthoquinones: Biomimetic Syntheses of Mollugin and Microphyllaquinone	Organic Letters	article	88
2013	Optical Control of TRPV1 Channels	Angewandte Chemie International Edition	article	87
2013	Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa	mBio	article	87
2010	Pharmacology of Ionotropic Glutamate Receptors: A Structural Perspective	Bioorganic & Medicinal Chemistry	article	87
2005	An Electrochemical Approach to the Guanacastepenes	Organic Letters	article	87
2018	Manipulating midbrain dopamine neurons and reward-related behaviors with light-controllable nicotinic acetylcholine receptors	eLife	article	86
2022	Medium-Chain Lipid Conjugation Facilitates Cell-Permeability and Bioactivity	Journal of the American Chemical Society	article	85
2019	Genetically Targeted Optical Control of an Endogenous G Protein-Coupled Receptor	Journal of the American Chemical Society	article	85
2012	Synthetic Approaches Toward Sesterterpenoids	Natural Product Reports	article	85
2008	Regulating Enzymatic Activity With a Photoswitchable Affinity Label	ChemBioChem	article	85
2020	A Lipid Photoswitch Controls Fluidity in Supported Bilayer Membranes	Langmuir	article	81
2003	Protein Surface Recognition by Rational Design: Nanomolar Ligands for Potassium Channels	Journal of the American Chemical Society	article	81
1999	Studies Towards the Total Synthesis of Halichlorine: Asymmetric Synthesis of the Spiroquinolizidine Subunit	Tetrahedron Letters	article	81
2008	Catalysis of 6π Electrocyclizations	Angewandte Chemie International Edition	article	80
2014	Controlling Epithelial Sodium Channels With Light Using Photoswitchable Amilorides	Nature Chemistry	article	79
2021	Optimized Photoactivatable Lipid Nanoparticles Enable Red Light Triggered Drug Release	Small	article	78
2004	Palladium-Catalyzed Couplings to Nucleophilic Heteroarenes: The Total Synthesis of (-)-Frondosin B	Tetrahedron	article	78
2019	New Players in Phototherapy: Photopharmacology and Bio-integrated Optoelectronics	Current Opinion in Chemical Biology	article	77
2017	PhoDAGs Enable Optical Control of Diacylglycerol-Sensitive Transient Receptor Potential Channels	Cell chemical biology	article	77
2011	Concise Total Synthesis of Variecolortide A and B Through an Unusual Hetero Diels-Alder Reaction	Angewandte Chemie International Edition	article	77
2017	Wild-type Monomeric α-Synuclein Can Impair Vesicle Endocytosis and Synaptic Fidelity via Tubulin Polymerization at the Calyx of Held	Journal of Neuroscience	article	76
2008	Biomimetic Synthesis of the Shimalactones	Organic Letters	article	76
2005	Mining the Tetraene Manifold: Total Synthesis of Complex Pyrones from Placobranchus ocellatus	Angewandte Chemie International Edition	article	76
2003	Synthetic Studies Toward the Guanacastepenes	Organic Letters	article	76
2002	The Total Synthesis of (–)-Amathaspiramide F	Angewandte Chemie International Edition	article	76
2015	A Red-Shifted Photochromic Sulfonylurea for the Remote Control of Pancreatic Beta Cell Function	Chemical Communications	article	75
2008	Biomimetic Synthesis of the IDO Inhibitors Exiguamine A and B	Nature Chemical Biology	article	75
1998	Synthesis of Enantiomerically Pure Morphine Alkaloids: The Hydrophenanthrene Route	The Journal of Organic Chemistry	article	75
1996	Formal Total Synthesis of (–)-Morphine by Cuprate Conjugate Addition	Angewandte Chemie International Edition in English	article	75
2008	Vinyl Quinones as Diels-Alder Dienes: Total Synthesis of (–)-Halenaquinone	Journal of the American Chemical Society	article	74
2020	Optical Manipulation of F-Actin with Photoswitchable Small Molecules	Journal of the American Chemical Society	article	73
2021	Optical Control of Targeted Protein Degradation	Cell chemical biology	article	72
2017	Photopharmacological Control of Bipolar Cells Restores Visual Function in Blind Mice	Journal of Clinical Investigation	article	71
2014	The in vivo Chemistry of Photoswitched Tethered Ligands	Current Opinion in Chemical Biology	article	71
2018	Optical Control of L-Type Ca2+ Channels Using a Diltiazem Photoswitch	Nature Chemical Biology	article	69
2017	Optical Control of AMPA Receptors Using a Photoswitchable Quinoxaline-2,3-dione Antagonist	Chemical Science	article	69
2011	An Efficient Synthesis of Loline Alkaloids	Nature Chemistry	article	69
2005	Total Synthesis of (–)-SNF4435 C and (+)-SNF4435 D	Organic Letters	article	68
2021	How Photoswitchable Lipids Affect the Order and Dynamics of Lipid Bilayers and Embedded Proteins	Journal of the American Chemical Society	article	67
2013	A Photoactive Porphyrin-Based Periodic Mesoporous Organosilica Thin Film	Journal of the American Chemical Society	article	67
2016	Optical Control of Neuronal Activity Using a Light Operated GIRK-Channel Opener (LOGO)	Chemical Science	article	66
2009	Calix[4]arene-Based Conical-Shaped Ligands for Voltage Dependent Potassium Channels	Proceedings of the National Academy of Sciences	article	66
2001	Concise Stereoselective Routes to Advanced Intermediates Related to Natural and Unnatural Pinnaic Acid	Angewandte Chemie	article	66
2019	A Biomimetic Synthesis Elucidates the Origin of Preuisolactone A	Journal of the American Chemical Society	article	65
2015	AzoCholine Enables Optical Control of Alpha 7 Nicotinic Acetylcholine Receptors in Neural Networks	ACS Chemical Neuroscience	article	65
2019	Body Mass Index in Multiple Sclerosis modulates ceramide-induced DNA methylation and disease course	EBioMedicine	article	64
1999	Insight into the Mechanism of the Saegusa Oxidation: Isolation of a Novel Palladium(0) Tetraolefin Complex	Angewandte Chemie International Edition	article	64
2012	A Total Synthesis Prompts the Structure Revision of Haouamine B	Journal of the American Chemical Society	article	63
2003	Development of Novel Lewis Acid Catalyzed Cycloisomerizations: Synthesis of Bicyclo[3.1.0] hexenes and Cyclopentenones	Tetrahedron	article	63
2005	Biomimetic Synthesis of Elysiapyrones A and B	Organic Letters	article	62
2016	Restoring Light Sensitivity in Blind Retinae Using a Photochromic AMPA Receptor Agonist	ACS Chemical Neuroscience	article	61
2015	Biomimetic Total Synthesis of Santalin Y	Angewandte Chemie International Edition	article	60
2018	SNAP-Tagged Nanobodies Enable Reversible Optical Control of a G Protein Coupled Receptor via a Remotely Tethered Photoswitchable Ligand	ACS Chemical Biology	article	59
2018	A (+)‐Larixol Congener with High Affinity and Subtype Selectivity toward TRPC6	ChemMedChem	article	59
2016	A Synthesis of (±)-Aplydactone	Angewandte Chemie International Edition	article	59
2014	Photochemical Formation of Intricarene	Nature Communications	article	59
2014	Biomimetic Synthesis of the Calcineurin Phosphatase Inhibitor Dibefurin	Angewandte Chemie International Edition	article	58
2014	Synthetic Retinal Analogs Modify the Spectral and Kinetic Characteristics of Microbial Rhodopsin Optogenetic Tools	Nature Communications	article	58
2016	Allosteric Optical Control of a Class B G-Protein-Coupled Receptor	Angewandte Chemie International Edition	article	57
2016	Expedient Synthesis of Lycopalhine A	Angewandte Chemie International Edition	article	57
2003	Biomimetic Synthesis of Pinnatal and Sterekunthal A	Journal of the American Chemical Society	article	57
2021	Cell Specific Photoswitchable Agonist for Reversible Control of Endogenous Dopamine Receptors	Nature Communications	article	56
2017	A Conia-Ene-Type Cyclization Under Basic Conditions Enables an Efficient Synthesis of (−)-Lycoposerramine R	Angewandte Chemie International Edition	article	56
2017	Specificity and Speed: Tethered Photopharmacology	Biochemistry	article	56
2017	Structure and Biosynthesis of Crocagins: Polycyclic Posttranslationally Modified Ribosomal Peptides from Chondromyces crocatus	Angewandte Chemie International Edition	article	56
2006	Photochemical Origin of SNF4435C/D and Formation of Orinocin through ‘Polyene Splicing	Angewandte Chemie International Edition	article	56
2003	Total Synthesis of (±)-Photodeoxytridachione Through a Lewis Acid Catalyzed Cyclization	Angewandte Chemie International Edition	article	56
2022	Concise Synthesis of Glycerophospholipids	The Journal of Organic Chemistry	article	55
2021	Controlling the Covalent Reactivity of a Kinase Inhibitor with Light.	Angewandte Chemie International Edition	article	55
2018	Total Synthesis of the Norhasubanan Alkaloid Stephadiamine	Journal of the American Chemical Society	article	55
2017	Remote Control of Glucose Homeostasis in vivo Using Photopharmacology	Scientific Reports	article	55
2005	Rational Design of a Chiral Pd(0)-Olefin Complex of Unprecedented Stability	Organometallics	article	55
2015	Inter-Kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway	PLoS Pathogens	article	54
2022	A Concise Synthesis of Tetrodotoxin	Science	article	53
2020	Photolipid Bilayer Permeability is Controlled by Transient Pore Formation	Langmuir	article	53
2010	Biomimetic Synthesis of (–)-Pycnanthuquinone C through the Diels-Alder Reaction of a Vinyl Quinone	Angewandte Chemie International Edition	article	53
2010	Toward the Total Synthesis of Maoecrystal V: Establishment of Contiguous Quaternary Stereocenters	Organic Letters	article	53
2003	Reductive Cyclization of d-Hydroxy Nitriles: A New Synthesis of Glycosylamines	Organic Letters	article	53
2021	Selective Photoswitchable Allosteric Agonist of a G Protein-Coupled Receptor	Journal of the American Chemical Society	article	52
2017	Optical Control of GPR40 Signaling in Pancreatic β-Cells	Chemical Science	article	52
2015	The α‐hydroxyketone LAI‐1 regulates motility, Lqs‐dependent phosphorylation signalling and gene expression of Legionella pneumophila	Molecular Microbiology	article	51
2006	Synthetic Studies Toward the Haouamines	Organic Letters	article	51
2022	Photoswitchable Serotonins for Optical Control of the 5-HT2A Receptor	Angewandte Chemie International Edition	article	50
2020	Optical Control of Lysophosphatidic Acid Signaling	Journal of the American Chemical Society	article	50
2017	Thiocarbonyl Ylide Chemistry Enables a Concise Synthesis of (±)-Hippolachnin A	Journal of the American Chemical Society	article	48
2014	Polytwistane	Chemistry - A European Journal	article	48
2007	Functionalized Azobenzenes Through Cross-Coupling with Organotrifluoroborates	Tetrahedron Letters	article	48
2022	Photopharmacological Control of Cell Signaling with Photoswitchable Lipids	Current Opinion in Pharmacology	article	46
2014	Total Synthesis of Sandresolide B and Amphilectolide	Organic Letters	article	46
2018	The Chemist and the Architect	Angewandte Chemie International Edition	article	45
2014	The Total Synthesis of (–)-Nitidasin	Angewandte Chemie International Edition	article	45
2021	Optical Control of Phosphatidic Acid Signaling	ACS Central Science	article	44
2020	Optical Control of Cytokine Production Using Photoswitchable Galactosylceramides	Chemistry - A European Journal	article	44
2020	Photohormones Enable Optical Control of the Peroxisome Proliferator-Activated Receptor γ (PPARγ)	Journal of Medicinal Chemistry	article	44
2019	Optical Manipulation of Sphingolipid Biosynthesis Using Photoswitchable Ceramides	eLife	article	44
2013	Biomimetic Synthesis of Santalin A, B and Santarubin A, B, the Major Colorants of Red Sandalwood	Angewandte Chemie International Edition	article	44
2010	Total Synthesis of Coralloidolides A, B, C, and E	Angewandte Chemie International Edition	article	44
2022	Optical Membrane Control with Red Light Enabled by Red-Shifted Photolipids	Langmuir	article	43
2012	A Unified Approach to trans-Hydrindane Sesterterpenoids	The Journal of Organic Chemistry	article	43
2018	Optical Tools for Understanding the Complexity of β-Cell Signalling and Insulin Release	Nature Reviews Endocrinology	article	42
2014	Biomimetic Synthesis of (±)-Merochlorin B	Organic Letters	article	42
2003	Intramolecular Diels-Alder Reactions of 5-Vinyl-1,3-cyclohexadienes	Organic Letters	article	42
2018	Biomimetic Synthesis of (+)‐Aspergillin PZ	Angewandte Chemie International Edition	article	41
2006	Development of a Friedel-Crafts Triflation	Organic Letters	article	41
2017	Photoswitchable Inhibitor of a Glutamate Transporter	ACS Chemical Neuroscience	article	40
2009	Photochrome Liganden für spannungsgesteuerte Kaliumkanäle	Angewandte Chemie	article	40
2000	On the Conformations of Halichlorine and the Pinnaic Acids: Nitrogen Inversion as a Possible Determinant of Biological Profile.	Helvetica Chimica Acta	article	40
2020	Optical Control of the Nuclear Bile Acid Receptor FXR with a Photohormone	Chemical Science	article	39
2017	Biomimetic Synthesis of Complex Flavonoids Isolated from Daemonorops ‘Dragon's Blood’	Angewandte Chemie International Edition	article	39
2014	Azobenzene-Based Inhibitors of Human Carbonic Anhydrase II	Beilstein Journal of Organic Chemistry	article	39
2004	The Total Synthesis of (–)-Crispatene	Proceedings of the National Academy of Sciences	article	39
2020	Reflections on Racemic Natural Products	Trends in Chemistry	article	38
2012	Total Synthesis of Exiguamines A and B Inspired by Catecholamine Chemistry	Chemistry - A European Journal	article	38
2007	Concise Synthesis of the Bacterial DNA Primase Inhibitor (+)-Sch 642305	Organic Letters	article	38
2014	A Step Toward Polytwistane: Synthesis and Characterization of C2-Symmetric Tritwistane	Organic & Biomolecular Chemistry	article	37
2013	Intramolecular Vinyl Quinone Diels–Alder Reactions: Asymmetric Entry to the Cordiachrome Core and Synthesis of (−)-Isoglaziovianol	Organic Letters	article	37
1997	The Phenanthrenone Approach to Opium Alkaloids: Formal Total Synthesis of Morphine by Sigmatropic Rearrangement	Synlett	article	37
2024	Identification of the Growth Cone as a Probe and Driver of Neuronal Migration in the Injured Brain	Nature Communications	article	36
2021	Cholesterol and Sphingomyelin are Critical for Fcγ Receptor-mediated Phagocytosis of Cryptococcus neoformans by Macrophages	Journal of Biological Chemistry	article	36
2021	Computational Exploration of the Mechanism of Critical Steps in the Biomimetic Synthesis of Preuisolactone A, and Discovery of New Ambimodal (5 + 2)/(4 + 2) Cy…	Journal of the American Chemical Society	article	36
2008	Mechanistic Investigations Into the Acid-Catalyzed Cyclization of a Vinyl Ortho-Quinone Methide	Chemistry - A European Journal	article	36
2018	Conditional and Reversible Activation of Class A and B G Protein-Coupled Receptors Using Tethered Pharmacology	ACS Central Science	article	35
2018	Total Synthesis of (±)–Exotine B	Organic Letters	article	35
2017	Total Syntheses of Cystobactamids and Structural Confirmation of Cystobactamid 919-2	Angewandte Chemie International Edition	article	35
2017	Development of a Photoswitchable Antagonist of NMDA Receptors	Tetrahedron	article	35
2015	Evolution of a Unified Strategy for Complex Sesterterpenoids: Progress toward Astellatol and Total Synthesis of (−)-Nitidasin	Chemistry - A European Journal	article	35
1998	New Ventures in the Construction of Complex Heterocycles: Synthesis of Morphine- and Hasubanan Alkaloids	ChemInform	article	35
2021	Short Photoswitchable Ceramides Enable Optical Control of Apoptosis	ACS Chemical Biology	article	34
2017	Asymmetric Synthesis of the Antiviral Diterpene Wickerol A	Journal of the American Chemical Society	article	34
2014	A Zinc Phthalocyanine-Based Periodic Mesoporous Organosilica Exhibiting Charge Transfer to Fullerenes	Chemistry - A European Journal	article	34
2012	Exploring the Pharmacology and Action Spectra of Photochromic Open Channel Blockers	ChemBioChem	article	34
2018	Optical Control of a Biological Reaction–Diffusion System	Angewandte Chemie International Edition	article	33
2012	An Approach to Aminonaphthoquinone Ansamycins Using a Modified Danishefsky Diene	Organic Letters	article	33
2005	Stereoselective Synthesis of the Cyercene A and Placidenes	Organic Letters	article	33
2002	A Practical Variant of the Claisen-Eschenmoser Rearrangement: Synthesis of Un-saturated Morpholine Amides	Synlett	article	33
2025	Photoswitchable phospholipids for the optical control of membrane processes, protein function, and drug delivery	Communications Materials	article	32
2012	Stereoselective Total Syntheses of Herbicidin C and Aureonuclemycin Through Late Stage Glycosylation	Angewandte Chemie International Edition	article	32
2012	The Crystal Structure of the Dess-Marin Periodinane	Beilstein Journal of Organic Chemistry	article	32
1999	Practical Synthesis of (–)-Morphine	Chirality	article	32
2024	Pixelated High-Q Metasurfaces for in Situ Biospectroscopy and Artificial Intelligence-Enabled Classification of Lipid Membrane Photoswitching Dynamics	ACS Nano	article	31
2018	Introduction: Optogenetics and Photopharmacology	Chemical Reviews	article	31
2017	Enantioselective Synthesis and Racemization of (–)-Sinoracutine	Angewandte Chemie International Edition	article	31
2017	Optical Control of GIRK Channels Using Visible Light	Organic & Biomolecular Chemistry	article	31
2013	A Photoswitchable Neurotransmitter Analogue Bound to its Receptor	Biochemistry	article	31
2006	Mapping the Chemistry of Highly Unsaturated Pyrone Polyketides	Synlett	article	30
2005	Photosensitized Conversion of 9,10-Deoxytridachione to Photodeoxytridachione	Organic Letters	article	30
2023	Optical Control of Neuronal Activities with Photoswitchable Nanovesicles	Nano Research	article	29
2020	Bioinspired Synthesis of (–)-PF-1018.	Angewandte Chemie International Edition	article	29
2019	Photopharmacologic Vision Restoration Reduces Pathological Rhythmic Field Potentials in Blind Mouse Retina	Scientific Reports	article	29
2005	Stereoselective Syntheses of the Bioactive Polypropionates Aureothin, N-Acetylaureothamine and Aureonitrile	Organic Letters	article	29
2022	Optical Control of Translation with a Puromycin Photoswitch	Journal of the American Chemical Society	article	28
2020	Light-induced Lipid Mixing Implies a Xausal role of lipid splay in membrane fusion	Biochimica et Biophysica Acta (BBA) - Biomembranes	article	28
2017	Selective Lithiation, Magnesiation and Zincation of Unsymmetrical Azobenzenes Using Continuous Flow	Organic Letters	article	28
2017	Total Synthesis of Lycopladine A and Carinatine A via a Base-Mediated Carbocyclization	The Journal of Organic Chemistry	article	28
2017	Optical Control of a Receptor-linked Guanylyl Cyclase Using a Photoswitchable Peptidic Hormone	Chemical Science	article	28
2011	Crocipodin, a Benzotropolone Pigment From the Mushroom Leccinum Crocipodium (Boletales)	Tetrahedron	article	28
2010	A Signal Processing Analysis of Purkinje Cells In Vitro	Frontiers in Neural Circuits	article	28
2023	Mapping Light Distribution in Tissue by Using MRI-Detectable Photosensitive Liposomes	Nature Biomedical Engineering	article	27
2021	Perfect and Defective 13C-Furan-Derived Nanothreads from Modest-Pressure Synthesis Analyzed by 13C NMR	Journal of the American Chemical Society	article	27
2020	Metabolic Tuning of Inhibition Regulates Hippocampal Neurogenesis in the Adult Brain	Proceedings of the National Academy of Sciences	article	27
2005	Dienophile Twisting and Substituent Effects Influence Reaction Rates of Intramolecular Diels-Alder Cycloadditions: a DFT Study	Journal of the American Chemical Society	article	27
2020	A Photoswitchable Inhibitor of the Human Serotonin Transporter	ACS Chemical Neuroscience	article	26
2013	Optical Modulation of Neurotransmission Using Calcium Photocurrents Through the Ion Channel LiGluR	Frontiers in Molecular Neuroscience	article	26
2025	Photoswitchable Diazocine Derivative for Adenosine A3 Receptor Activation in Psoriasis	Journal of the American Chemical Society	article	25
2018	A Versatile Bis-Allylboron Reagent for the Stereoselective Synthesis of Chiral Diols	Angewandte Chemie International Edition	article	25
2018	A Predictive Approach for the Optical Control of Carbonic Anhydrase II Activity	ACS Chemical Biology	article	25
2014	Relative Positioning of Classical Benzodiazepines to the γ2‑Subunit of GABA-A Receptors	ACS Chemical Biology	article	25
2023	Structural Diversity of Photoswitchable Sphingolipids for Optodynamic Control of Lipid Microdomains	Biophysical Journal	article	24
2018	Toward (−)-Enterocin: An Improved Cuprate Barbier Protocol to Overcome Strain and Sterical Hindrance	Organic Letters	article	24
2005	Concise Synthesis of (±)-Smenochromene D (Likonide B)	Synlett	article	24
2022	Postsynthetic Photocontrol of Giant Liposomes via Fusion-Based Photolipid Doping	Langmuir	article	23
2020	Transformation of Receptor Tyrosine Kinases into Glutamate Receptors and Photoreceptors	Angewandte Chemie International Edition	article	23
2019	Two-Dimensional Electronic Spectroscopy Reveals the Spectral Dynamics of Förster Resonance Energy Transfer	Chem	article	23
2018	Selective Synthesis of Divergolide I	Journal of the American Chemical Society	article	23
2013	Studies toward the Biomimetic Total Synthesis of (-)-PF-1018	Organic Letters	article	23
2011	Synthetic Studies Toward A-74528	Organic Letters	article	23
2024	Optical Control of G-Actin with a Photoswitchable Latrunculin	Journal of the American Chemical Society	article	22
2022	Optical Control of Mitosis with a Photoswitchable Eg5 Inhibitor	Angewandte Chemie International Edition	article	22
2022	Photoactivation of a Mechanosensitive Channel	Frontiers in Molecular Biosciences	article	22
2017	Unravelling Photochemical Relationships Amongst Natural Products from Aplysia dactylomela	ACS Central Science	article	22
2015	Richard Willstätter and the 1915 Nobel Prize in Chemistry	Angewandte Chemie International Edition	article	22
2018	Optical Control of a Delayed Rectifier and a Two-Pore Potassium Channel with a Photoswitchable Bupivacaine	ACS Chemical Neuroscience	article	21
2010	Total Synthesis of Newbouldine via Reductive N-N Bond Formation	Tetrahedron	article	21
2002	Borane-Ammonia Complexes Stabilized by Hydrogen Bonding	Organic Letters	article	21
1996	Formale Totalsynthese von (−)‐Morphin über konjugierte Cuprataddition	Angewandte Chemie	article	21
2020	Photopharmacological Control of Lipid Function	Methods in enzymology on CD-ROM/Methods in enzymology	article	20
2018	Reversible Optical Control of F1F0-ATP Synthase Using Photoswitchable Inhibitors	FEBS Letters	article	20
2013	Total Synthesis of Herbicidin C and Aureonuclemycin: Impasses and New Avenues	The Journal of Organic Chemistry	article	20
2010	Theoretical Investigation of the Rubicordifolin Cascade	Organic Letters	article	20
2008	Conjugate Addition of Allyl Stannanes with Concomitant Triflation	Organic Letters	article	20
2023	Optical Control of Dopamine D2-like Receptors with Cell-specific Fast-Relaxing Photoswitches	Journal of the American Chemical Society	article	19
2021	A Photohormone for Light-Dependent Control of PPARα in Live Cells	Journal of Medicinal Chemistry	article	19
2019	Synthesis and Biological Evaluation of (±)-Hippolachnin and Analogs	The Journal of Antibiotics	article	19
2014	Finding function and form	Natural Product Reports	article	19
2003	Enzymatic Desymmetrization of a Centrosymmetric Diacetate	Tetrahedron Asymmetry	article	19
2023	Photoactivated Protein Degrader for Optical Control of Synaptic Function	ACS Chemical Neuroscience	article	18
2022	Next Generation Opto-Jasplakinolides Enable Local Remodeling of Actin Networks	Angewandte Chemie International Edition	article	18
2015	Synthetic Studies Toward Polytwistane Hydrocarbon Nanorods	The Journal of Organic Chemistry	article	18
2006	Photochemische Herkunft der Immunsuppressiva SNF4435C/D und Bildung von Orinocin durch “Polyen‐Splicing”	Angewandte Chemie	article	18
1996	Stereoselective Insertion of Ketenes into O,O-Acetals: Synthesis of b-Alkoxy Esters and 1,4- dioxepanones	Angewandte Chemie International Edition in English	article	17
2013	Optical Control of Calcium-Regulated Exocytosis	Biochimica et Biophysica Acta (BBA) - General Subjects	article	16
2019	A Biomimetic Approach Toward Enterocin and Deoxyenterocin	The Journal of Organic Chemistry	article	15
2018	Azomethine Ylide Cycloaddition Approach toward Dendrobine: Synthesis of 5-Deoxymubironine C	The Journal of Organic Chemistry	article	15
2025	Biomimetic Synthesis of Azorellolide via Cyclopropylcarbinyl Cation Chemistry	Journal of the American Chemical Society	article	14
2025	Reaction Development: A Student's Checklist	Chemical Society Reviews	article	14
2022	Photoswitchable Isoprenoid Lipids Enable Optical Control of Peptide Lipidation	ACS Chemical Biology	article	14
2021	Optical Control of Adenosine-Mediated Pain Modulation	Bioconjugate Chemistry	article	14

The 300 most cited are listed; 72 more are not.