Trackademia

Welcome to Trackademia

The idea behind Trackademia is to build on existing academic databases like Google Scholar and OpenAlex so that you can trust the data and use it for whatever you want. That comes down to two things.

More data, and more ways to use it. We aggregate publication data from every major source into a single dataset and add information pulled from faculty CVs. Then we let you slice it however you want: choose which sources to build from, write your own formulas, weight journals, adjust for department size.

More accurate, and honest about where it isn’t. We focus on a smaller set of schools so we can verify everything carefully. Faculty lists come from department websites rather than being inferred from publication records, so we know who should be in the data before we go looking. When we can’t find data on someone, we record the gap instead of dropping them. Every number comes with a coverage rate you can check against ground truth.

Everything in Trackademia is built from seven units. AI merges duplicate records across sources and tags each publication so these categories hold up:

  • Publication — citation counts, authors, journal, peer review status, and more
  • Publication group — versions of the same work combined into one entity, such as a working paper and the article it became
  • Academic
  • Department
  • University
  • Field
  • Journal

There are two modes. In Database mode you browse the underlying records and filter by any of the seven units. In Analytics mode you get graphs and comparisons, and you switch views to compare two departments, compare one department against the average of the others, or see them all at once. Tabs let you focus on a particular level of the data.

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Academic

David W. Christianson

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Academic

RankUnknown
As ofnot recorded
DepartmentPenn Chemistry
UniversityPenn
FieldChemistry
Scholarprofile

Totals

Publications99
Citations24,312
h-index100 · Scholar
Citations per year in post
Years in postno first year on the CV

Coverage

Works with a count99 of 99
Share100%

Top venues 25 venues

The 8 holding the most of these works; 17 more hold at least one.

Biochemistry17
Journal of the American Chemical Society15
Proceedings of the National Academy of Scienc…13
Journal of Biological Chemistry7
Journal of Medicinal Chemistry5
Protein Science4
Accounts of Chemical Research3
Current Opinion in Structural Biology3

Publications per year

Works this academic published in each year, by the year each work appeared; an undated work is in no year, and a work two colleagues wrote counts for each of them. The kind, works and year filters decide which works are here at all.

Citations per year

Citations received in each year, from this academic’s verified Scholar profile, which counts every citation to everything they ever wrote: no publication filter reaches this line - not the kinds, not the works switch, not the year window on publication - and no journal weight either. It is a profile total, so it does not match the works listed below.

Publications 99 works

Every work these filters select, most cited first and the works with no count at the end: a work nobody has a figure for is unknown, never a zero to be ranked among the works that have one, and it prints an em dash. Each figure is that work’s own citations - Scholar’s count where there is one, else OpenAlex’s - and is not weighted.

YearTitleVenueKindCitations
2017Structural and chemical biology of terpenoid cyclasesChemical Reviewsarticle1,406
2006Structural biology and chemistry of the terpenoid cyclasesChemical Reviewsarticle955
1989Carboxypeptidase aAccounts of Chemical Researcharticle905
2012HDAC8 mutations in Cornelia de Lange syndrome affect the cohesin acetylation cycleNaturearticle748
1996Carbonic anhydrase: evolution of the zinc binding site by nature and by designAccounts of Chemical Researcharticle629
2016Histone deacetylase 6 structure and molecular basis of catalysis and inhibitionNature Chemical Biologyarticle606
1991Structural biology of zincAdvances in protein chemistryarticle597
1997Crystal structure of pentalenene synthase: mechanistic insights on terpenoid cyclization reactions in biologySciencearticle565
1996Structure of a unique binuclear manganese cluster in arginaseNaturearticle558
1999Catalysis by metal-activated hydroxide in zinc and manganese metalloenzymesAnnual Review of Biochemistryarticle479
2001Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cellsProceedings of the National Academy of Sciencesarticle440
2011Taxadiene synthase structure and evolution of modular architecture in terpene biosynthesisNaturearticle426
2002Bornyl diphosphate synthase: structure and strategy for carbocation manipulation by a terpenoid cyclaseProceedings of the National Academy of Sciencesarticle419
2008Unearthing the roots of the terpenomeCurrent Opinion in Chemical Biologyarticle389
2011Structure, mechanism, and inhibition of histone deacetylases and related metalloenzymesCurrent Opinion in Structural Biologyarticle381
1990Hydrogen bond stereochemistry in protein structure and functionJournal of Molecular Biologyarticle373
2001Structure of trichodiene synthase from Fusarium sporotrichioides provides mechanistic inferences on the terpene cyclization cascadeProceedings of the National Academy of Sciencesarticle348
2009Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old ratsJournal of Applied Physiologyarticle313
2008Endothelial arginase II: a novel target for the treatment of atherosclerosisCirculation Researcharticle304
1999Detoxification of environmental mutagens and carcinogens: structure, mechanism, and evolution of liver epoxide hydrolaseProceedings of the National Academy of Sciencesarticle288
1997Structural chemistry and biology of manganese metalloenzymesarticle280
1991Unexpected pH-dependent conformation of His-64, the proton shuttle of carbonic anhydrase IIJournal of the American Chemical Societyarticle275
2017ARID1A-mutated ovarian cancers depend on HDAC6 activityNature Cell Biologyarticle271
2007Inducible NO Synthase–Dependent S-Nitrosylation and Activation of Arginase1 Contribute to Age-Related Endothelial DysfunctionCirculation Researcharticle252
2008Structural Studies of Human Histone Deacetylase 8 and Its Site-Specific Variants Complexed with Substrate and Inhibitors,Biochemistryarticle251
1998Protein component of the ribozyme ribonuclease P alters substrate recognition by directly contacting precursor tRNAProceedings of the National Academy of Sciencesarticle248
2004Structure of Human Epoxide Hydrolase Reveals Mechanistic Inferences on Bifunctional Catalysis in Epoxide and Phosphate Ester Hydrolysis,Biochemistryarticle238
1994Two-site binding of phenol in the active site of human carbonic anhydrase II: structural implications for substrate associationJournal of the American Chemical Societyarticle238
1994Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loopNature Structural Biologyarticle238
2005Crystal structure of human arginase I at 1.29-Å resolution and exploration of inhibition in the immune responseProceedings of the National Academy of Sciencesarticle237
2017Histone deacetylase 10 structure and molecular function as a polyamine deacetylaseNature Communicationsarticle233
2000Crystal structure determination of aristolochene synthase from the blue cheese mold, Penicillium roquefortiJournal of Biological Chemistryarticle224
1999Arginase–boronic acid complex highlights a physiological role in erectile functionNature Structural Biologyarticle224
1998Ribonuclease P protein structure: evolutionary origins in the translational apparatusSciencearticle223
2001Probing Erectile Function: S-(2-Boronoethyl)-l-Cysteine Binds to Arginase as a Transition State Analogue and Enhances Smooth Muscle Relaxation in Human Penile …Biochemistryarticle222
2008Arginase and vascular agingJournal of Applied Physiologyarticle219
2011Structure and mechanism of the diterpene cyclase ent-copalyl diphosphate synthaseNature Chemical Biologyarticle218
2014Loss-of-function HDAC8 mutations cause a phenotypic spectrum of Cornelia de Lange syndrome-like features, ocular hypertelorism, large fontanelle and X-linked …Human Molecular Geneticsarticle215
1989Carboxylate-histidine-zinc interactions in protein structure and functionJournal of the American Chemical Societyarticle213
2017Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitorsProceedings of the National Academy of Sciencesarticle210
1991Altering the mouth of a hydrophobic pocket. Structure and kinetics of human carbonic anhydrase II mutants at residue Val-121.Journal of Biological Chemistryarticle207
2003Crystal structure of LpxC, a zinc-dependent deacetylase essential for endotoxin biosynthesisProceedings of the National Academy of Sciencesarticle205
1996Crystal structure of the secretory form of membrane-associated human carbonic anhydrase IV at 2.8-Å resolutionProceedings of the National Academy of Sciencesarticle203
2011Structural basis of the antiproliferative activity of largazole, a depsipeptide inhibitor of the histone deacetylasesJournal of the American Chemical Societyarticle200
2002Pentalenene synthase. Analysis of active site residues by site-directed mutagenesisJournal of the American Chemical Societyarticle200
2005Arginase: structure, mechanism, and physiological role in male and female sexual arousalAccounts of Chemical Researcharticle196
2003Human Arginase II: Crystal Structure and Physiological Role in Male and Female Sexual Arousal,Biochemistryarticle193
1993Purification and characterization of Klebsiella aerogenes UreE protein: A nickel‐binding protein that functions in urease metallocenter assemblyProtein Sciencearticle192
2010Structure of epi-isozizaene synthase from Streptomyces coelicolor A3 (2), a platform for new terpenoid cyclization templatesBiochemistryarticle188
2009Cryptophane xenon-129 nuclear magnetic resonance biosensors targeting human carbonic anhydraseJournal of the American Chemical Societyarticle186
2007X-ray crystal structure of aristolochene synthase from Aspergillus terreus and the evolution of templates for the cyclization of farnesyl diphosphateBiochemistryarticle178
2000Contribution of fluorine to protein− ligand affinity in the binding of fluoroaromatic inhibitors to carbonic anhydrase IIJournal of the American Chemical Societyarticle176
1997Inhibition of Mn2+2-Arginase by Borate Leads to the Design of a Transition State Analogue Inhibitor, 2(S)-Amino-6-boronohexanoic AcidJournal of the American Chemical Societyarticle176
2010Trinuclear metal clusters in catalysis by terpenoid synthasesarticle172
2019Structure, mechanism, and inhibition of the zinc-dependent histone deacetylasesCurrent Opinion in Structural Biologyarticle168
2010Arginase I suppresses IL-12/IL-23p40–driven intestinal inflammation during acute schistosomiasisThe Journal of Immunologyarticle168
2000Binding of alkylurea inhibitors to epoxide hydrolase implicates active site tyrosines in substrate activationJournal of Biological Chemistryarticle165
1998Managing and manipulating carbocations in biology: terpenoid cyclase structure and mechanismCurrent Opinion in Structural Biologyarticle160
1986X-ray crystallographic investigation of substrate binding to carboxypeptidase A at subzero temperature.Proceedings of the National Academy of Sciencesarticle157
1995X-ray crystallographic studies of engineered hydrogen bond networks in a protein-zinc binding siteJournal of the American Chemical Societyarticle156
1994Identification of two hydrophobic patches in the active-site cavity of human carbonic anhydrase II by solution-phase and solid-state studies and their use in t…Journal of Medicinal Chemistryarticle154
1995Secondary interactions significantly removed from the sulfonamide binding pocket of carbonic anhydrase II influence inhibitor binding constantsJournal of Medicinal Chemistryarticle151
2000Biochemical evidence for the involvement of tyrosine in epoxide activation during the catalytic cycle of epoxide hydrolaseJournal of Biological Chemistryarticle150
1995Structure determination of murine mitochondrial carbonic anhydrase V at 2.45-A resolution: implications for catalytic proton transfer and inhibitor design.Proceedings of the National Academy of Sciencesarticle149
2004Expression, assay, and structure of the extracellular domain of murine carbonic anhydrase XIVJournal of Biological Chemistryarticle143
1993Structural and functional importance of a conserved hydrogen bond network in human carbonic anhydrase II.Journal of Biological Chemistryarticle142
2009Crystal structure of (+)-δ-cadinene synthase from Gossypium arboreum and evolutionary divergence of metal binding motifs for catalysisBiochemistryarticle139
1997Novel binding mode of hydroxamate inhibitors to human carbonic anhydrase IIJournal of the American Chemical Societyarticle139
1996Reversal of the hydrogen bond to zinc ligand histidine-119 dramatically diminishes catalysis and enhances metal equilibration kinetics in carbonic anhydrase IIBiochemistryarticle139
2010Structure of isoprene synthase illuminates the chemical mechanism of teragram atmospheric carbon emissionJournal of Molecular Biologyarticle136
1997Histidine→ carboxamide ligand substitutions in the zinc binding site of carbonic anhydrase II alter metal coordination geometry but retain catalytic activityBiochemistryarticle134
2008Directing noble metal ion chemistry within a designed ferritin proteinBiochemistryarticle132
2007Roots of biosynthetic diversitySciencearticle132
2013Development of potent and selective indomethacin analogues for the inhibition of AKR1C3 (Type 5 17β-hydroxysteroid dehydrogenase/prostaglandin F synthase) in c…Journal of Medicinal Chemistryarticle131
1998Structures of murine carbonic anhydrase IV and human carbonic anhydrase II complexed with brinzolamide: Molecular basis of isozyme‐drug discriminationProtein Sciencearticle131
2006Human soluble epoxide hydrolase: Structural basis of inhibition by 4‐(3‐cyclohexylureido)‐carboxylic acidsProtein Sciencearticle130
1991Engineering the hydrophobic pocket of carbonic anhydrase IIBiochemistryarticle130
1998Structural analysis of inhibitor binding to human carbonic anhydrase IIProtein Sciencearticle124
2002Combinatorial computational method gives new picomolar ligands for a known enzymeProceedings of the National Academy of Sciencesarticle123
2003Arginase and autoimmune inflammation in the central nervous systemarticle119
2000Arginase: a binuclear manganese metalloenzymearticle119
2019Synthesis and biological investigation of phenothiazine-based benzhydroxamic acids as selective histone deacetylase 6 inhibitorsJournal of Medicinal Chemistryarticle118
1991Biological recognition of phosphate and sulfateJournal of Biological Chemistryarticle117
2018Histone deacetylase 6-selective inhibitors and the influence of capping groups on hydroxamate-zinc denticityJournal of Medicinal Chemistryarticle116
2002Crystal structure of F65A/Y131C-methylimidazole carbonic anhydrase V reveals architectural features of an engineered proton shuttleBiochemistryarticle116
2021Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sitesNature Communicationsarticle115
1997Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic functionBiochemistryarticle114
1987Mechanism of carboxypeptidase A: hydration of a ketonic substrate analogue.Proceedings of the National Academy of Sciencesarticle113
1986Complex between carboxypeptidase A and a possible transition-state analog: mechanistic inferences from high-resolution x-ray structures of enzyme-inhibitor com…Journal of the American Chemical Societyarticle112
2001Mechanistic and Metabolic Inferences from the Binding of Substrate Analogues and Products to Arginase,Biochemistryarticle111
2006Ultrahigh resolution crystal structures of human carbonic anhydrases I and II complexed with “two-prong” inhibitors reveal the molecular basis of high affinityJournal of the American Chemical Societyarticle108
2002X-ray Crystal Structures of D100E Trichodiene Synthase and Its Pyrophosphate Complex Reveal the Basis for Terpene Product Diversity,Biochemistryarticle107
2001Fluoroaromatic− Fluoroaromatic Interactions between Inhibitors Bound in the Crystal Lattice of Human Carbonic Anhydrase IIJournal of the American Chemical Societyarticle106
2013Crystal structure of arginase from Leishmania mexicana and implications for the inhibition of polyamine biosynthesis in parasitic infectionsNitric Oxidearticle104
2010Structures of metal-substituted human histone deacetylase 8 provide mechanistic inferences on biological functionBiochemistryarticle103
1990Stereochemistry of phosphate-Lewis acid interactions: implications for nucleic acid structure and recognitionJournal of the American Chemical Societyarticle101
1999Biochemical and functional profile of a newly developed potent and isozyme-selective arginase inhibitorJournal of Pharmacology and Experimental Therapeuticsarticle100
1996Structure-based design of a sulfonamide probe for fluorescence anisotropy detection of zinc with a carbonic anhydrase-based biosensorJournal of the American Chemical Societyarticle100
1991Conformational mobility of His-64 in the Thr-200. fwdarw. Ser mutant of human carbonic anhydrase IIBiochemistryarticle100