Bruce Ganem
Academic
Totals
Coverage
Top venues 22 venues
The 8 holding the most of these works; 14 more hold at least one.
Publications per year
Works this academic published in each year, by the year each work appeared; an undated work is in no year, and a work two colleagues wrote counts for each of them. The kind, works and year filters decide which works are here at all.
Citations per year
Citations received in each year, from this academic’s verified Scholar profile, which counts every citation to everything they ever wrote: no publication filter reaches this line - not the kinds, not the works switch, not the year window on publication - and no journal weight either. It is a profile total, so it does not match the works listed below.
Publications 99 works
Every work these filters select, most cited first and the works with no count at the end: a work nobody has a figure for is unknown, never a zero to be ranked among the works that have one, and it prints an em dash. Each figure is that work’s own citations - Scholar’s count where there is one, else OpenAlex’s - and is not weighted.
| Year | Title | Venue | Kind | Citations |
|---|---|---|---|---|
| 2009 | Strategies for innovation in multicomponent reaction design | Accounts of Chemical Research | article | 1,404 |
| 1968 | New methods for the oxidation of aldehydes to carboxylic acids and esters | Journal of the American Chemical Society | article | 801 |
| 1991 | Detection of noncovalent receptor-ligand complexes by mass spectrometry | Journal of the American Chemical Society | article | 741 |
| 1991 | Observation of noncovalent enzyme-substrate and enzyme-product complexes by ion-spray mass spectrometry | Journal of the American Chemical Society | article | 464 |
| 1996 | Identification of two functionally different classes of exocellulases | Biochemistry | article | 392 |
| 1996 | Inhibitors of carbohydrate-processing enzymes: Design and synthesis of sugar-shaped heterocycles | Accounts of Chemical Research | article | 362 |
| 1986 | Synthetically useful reactions with metal boride and aluminide catalysts | Chemical Reviews | article | 351 |
| 1984 | Mechanism and synthetic utility of boron trifluoride etherate-promoted organolithium additions | Journal of the American Chemical Society | article | 323 |
| 1995 | Atomic structure of the buried catalytic pocket of Escherichia coli chorismate mutase | Journal of the American Chemical Society | article | 300 |
| 1974 | Ferric chloride in acetic anhydide. Mild and versatile reagent for the cleavage of ethers | The Journal of Organic Chemistry | article | 288 |
| 1978 | From glucose to aromatics: recent developments in natural products of the shikimic acid pathway | Tetrahedron | article | 284 |
| 1984 | An exceptionally mild deprotection of phthalimides | Tetrahedron Letters | article | 281 |
| 1973 | . alpha.-Silylated vinyl ketones. New class of reagents for the annelation of ketones | Journal of the American Chemical Society | article | 245 |
| 1987 | The mechanism of rearrangement of chorismic acid and related compounds | Journal of the American Chemical Society | article | 242 |
| 1995 | Structural and stereochemical studies of potent inhibitors of glucosylceramide synthase and tumor cell growth. | Journal of Lipid Research | article | 235 |
| 1976 | Lithium and potassium trialkylborohydrides. Reagents for direct reduction of. alpha.,. beta.-unsaturated carbonyl compounds to synthetically versatile enolate… | The Journal of Organic Chemistry | article | 231 |
| 1982 | Mechanism of sodium borohydride-cobaltous chloride reductions | Journal of the American Chemical Society | article | 207 |
| 1982 | New chemistry of naturally occurring polyamines | Accounts of Chemical Research | article | 186 |
| 1986 | Studies on the mechanism of transition-metal-assisted sodium borohydride and lithium aluminum hydride reductions | Journal of the American Chemical Society | article | 183 |
| 1993 | Detection of oligonucleotide duplex forms by ion-spray mass spectrometry | Tetrahedron Letters | article | 180 |
| 1995 | Recognition of cell‐wall peptide ligands by vancomycin group antibiotics: Studies using ion spray mass spectrometry | Journal of Mass Spectrometry | article | 175 |
| 1996 | The mechanism of the Claisen rearrangement: déjà vu all over again | Angewandte Chemie International Edition in English | article | 169 |
| 1995 | New insight into the catalytic mechanism of chorismate mutases from structural studies | Chemistry & Biology | article | 166 |
| 1993 | Studies on heme binding in myoglobin, hemoglobin, and cytochrome c by ion spray mass spectrometry | Journal of the American Society for Mass Spectrometry | article | 160 |
| 1985 | Rapid and efficient reduction of aliphatic nitro compounds to amines | Tetrahedron Letters | article | 160 |
| 1993 | Amidine, amidrazone, and amidoxime derivatives of monosaccharide aldonolactams: synthesis and evaluation as glycosidase inhibitors | Journal of the American Chemical Society | article | 156 |
| 1984 | Epoxides as alkene protecting groups. A mild and efficient deoxygenation | Tetrahedron Letters | article | 150 |
| 1985 | Efficient preparation of enantiomerically pure cyclic aminoalditols, total synthesis of 1-deoxynojirimycin and 1-deoxymannojirimycyn | Tetrahedron Letters | article | 149 |
| 2001 | Asymmetric total synthesis of (−)-α-kainic acid using an enantioselective, metal-promoted ene cyclization | Organic Letters | article | 141 |
| 1998 | Chorismate mutase-prephenate dehydratase from Escherichia coli: study of catalytic and regulatory domains using genetically engineered proteins | Journal of Biological Chemistry | article | 141 |
| 1981 | Catalyzed insertion reactions of substituted α-diazoesters. A new synthesis of cis-enoates | Tetrahedron Letters | article | 141 |
| 1996 | Characterization of Benzodiazepine “Combinatorial” Chemical Libraries by On-Line Immunoaffinity Extraction, Coupled Column HPLC− Ion Spray Mass Spectrometry− T… | Analytical Chemistry | article | 140 |
| 1990 | Potent, broad-spectrum inhibition of glycosidases by an amidine derivative of D-glucose | Journal of the American Chemical Society | article | 138 |
| 1997 | A new approach to porphobilinogen and its analogs | Tetrahedron | article | 133 |
| 1981 | A new protecting group for amines. Synthesis of anticapsin from L-tyrosine | Tetrahedron Letters | article | 133 |
| 1991 | Mimicking the glucosidase transition state: shape/charge considerations | Journal of the American Chemical Society | article | 131 |
| 1993 | Mass spectrometric studies on noncovalent dimers of leucine zipper peptides | Journal of the American Chemical Society | article | 128 |
| 1984 | Total syntheses of (+)-castanospermine and (+)-deoxynojirimycin | Tetrahedron Letters | article | 128 |
| 1975 | Biological spin labels as organic reagents. Oxidation of alcohols to carbonyl compounds using nitroxyls | The Journal of Organic Chemistry | article | 124 |
| 2010 | Dihydropyrimidinone positive modulation of δ-subunit-containing γ-aminobutyric acid type A receptors, including an epilepsy-linked mutant variant | Biochemistry | article | 122 |
| 1987 | Synthesis of (+)-1, 5-dideoxy-1, 5-imino-d-galactitol, a potent α-d-galactosidase inhibitor | — | article | 122 |
| 2006 | Studies on the Biginelli reaction: a mild and selective route to 3, 4-dihydropyrimidin-2 (1H)-ones via enamine intermediates | Tetrahedron Letters | article | 119 |
| 1990 | Ready oxidation of halides to aldehydes using trimethylamine N-oxide in dimethylsulfoxide | Tetrahedron Letters | article | 117 |
| 1996 | Reduction of secondary carboxamides to imines | The Journal of Organic Chemistry | article | 116 |
| 1973 | Spiroannelation of enol ethers of cyclic 1, 3-diketones. Simple stereospecific synthesis of. beta.-vetivone | Journal of the American Chemical Society | article | 116 |
| 1994 | Synthetic studies on Mannostatin A and its derivatives: a new family of glycoprotein processing inhibitors | Journal of the American Chemical Society | article | 115 |
| 1992 | Cytostasis induced in L1210 murine leukaemia cells by the S-adenosyl-l-methionine decarboxylase inhibitor 5′-([(Z)-4-amino-2-butenyl]methylamino)-5 … | Biochemical Journal | article | 111 |
| 1982 | A new. beta.-lactam synthesis | Journal of the American Chemical Society | article | 111 |
| 1995 | Kukoamine A and other hydrophobic acylpolyamines: potent and selective inhibitors of Crithidia fasciculata trypanothione reductase | Biochemical Journal | article | 110 |
| 1987 | Chemistry of naturally occurring polyamines. 11. Unsaturated spermidine and spermine derivatives | The Journal of Organic Chemistry | article | 109 |
| 1988 | Effectiveness of natural and synthetic complexes of porin and O polysaccharide as vaccines against Brucella abortus in mice | Infection and Immunity | article | 106 |
| 1979 | 2-Hydroperoxyhexafluoro-2-propanol. A low-cost, catalytic oxidant for synthesis and a structural analog of naturally occurring flavin hydroperoxides | Journal of the American Chemical Society | article | 103 |
| 1978 | A new synthesis of amides and macrocyclic lactams | The Journal of Organic Chemistry | article | 101 |
| 2002 | Total synthesis of (-)-vertinolide. A general approach to chiral tetronic acids and butenolides from allylic alcohols | The Journal of Organic Chemistry | article | 100 |
| 1993 | Reductive deoxygenation by Cp2ZrHCl: Selective formation of imines via zirconation/hydrozirconation of amides | Tetrahedron Letters | article | 100 |
| 1990 | A new family of five-carbon iminoalditols which are potent glycosidase inhibitors | Tetrahedron Letters | article | 99 |
| 2002 | Metal-promoted variants of the Passerini reaction leading to functionalized heterocycles | Organic Letters | article | 94 |
| 1985 | BF3-etherate promoted alkylation of aziridines with organocopper reagents: A new synthesis of amines | Tetrahedron Letters | article | 94 |
| 1999 | Structure and Total Synthesis of HF-7, a Neuroactive Glyconucleoside Disulfate from the Funnel-Web Spider Hololena curta | Journal of the American Chemical Society | article | 91 |
| 1996 | Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors | Bioorganic & Medicinal Chemistry | article | 89 |
| 1983 | Chemistry of naturally occurring polyamines. 8. Total synthesis of (+)-hypusine | The Journal of Organic Chemistry | article | 88 |
| 2007 | Paclitaxel from primary taxanes: a perspective on creative invention in organozirconium chemistry | The Journal of Organic Chemistry | article | 87 |
| 1975 | Conjugate reduction and reductive alkylation of. alpha.,. beta.-unsaturated cyclohexenones using potassium tri-sec-butylborohydride | The Journal of Organic Chemistry | article | 87 |
| 1994 | Studies of non‐covalent interactions of actinomycin D with single‐stranded oligodeoxynucleotides by ion spray mass spectrometry and tandem mass spectrometry | — | article | 84 |
| 1985 | Syn-stereoselective epoxidation of allylic ethers using CF3CO3H. | Tetrahedron Letters | article | 84 |
| 1980 | The chemistry of naturally occurring polyamines. 1. Total synthesis of celacinnine, celabenzine and maytenine | The Journal of Organic Chemistry | article | 83 |
| 2003 | 3‐Trimethylsilyl‐3‐Buten‐2‐one: AM ichael acceptor: 3‐Buten‐2‐one, 3‐(trimethylsilyl)‐ | Organic Syntheses | article | 82 |
| 1982 | Shikimate-derived metabolites. 11. A total synthesis of (.+-.)-chorismic acid | Journal of the American Chemical Society | article | 81 |
| 1987 | Chelate selectivity in chelation-controlled allylations. A new synthesis of castanospermine and other bioactive indolizidine alkaloids | The Journal of Organic Chemistry | article | 79 |
| 2003 | Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts | Journal of the American Chemical Society | article | 78 |
| 2001 | Polyamines with N-(3-phenylpropyl) substituents are effective competitive inhibitors of trypanothione reductase and trypanocidal agents | Bioorganic & Medicinal Chemistry Letters | article | 77 |
| 1988 | A potent new class of active-site-directed glycosidase inactivators | Journal of the American Chemical Society | article | 77 |
| 1988 | An improved synthesis of D-perosamine and some derivatives | — | article | 76 |
| 1991 | Enantioselective synthesis of mannostatin A: a new glycoprotein processing inhibitor | Journal of the American Chemical Society | article | 75 |
| 1983 | Improved oxidation of amines with dibenzoyl peroxide | Synthesis | article | 73 |
| 1974 | Silver-assisted dimethylsulfoxide oxidations; an improved synthesis of aldehydes and ketones | Tetrahedron Letters | article | 72 |
| 1986 | Chemistry of naturally occurring polyamines. 10. Nonmetabolizable derivatives of spermine and spermidine | The Journal of Organic Chemistry | article | 70 |
| 1998 | Pseudoceratidine, a marine natural product with antifouling activity: synthetic and biological studies | Tetrahedron | article | 69 |
| 1995 | Kinetic monitoring of enzymatic reactions in real time by quantitative high-performance liquid chromatography-mass spectrometry | Analytical Biochemistry | article | 68 |
| 2001 | Selective fowler reductions: asymmetric total syntheses of isofagomine and other 1-azasugars from methyl nicotinate | Organic Letters | article | 66 |
| 1994 | Analysis of the energetics of gas-phase immunophilin-ligand complexes by ion spray mass spectrometry | Journal of the American Chemical Society | article | 66 |
| 1999 | Regulation of Phenylalanine Biosynthesis. Studies on the Mechanism of Phenylalanine Binding and Feedback Inhibition in the Escherichia coli P-Protein | Biochemistry | article | 65 |
| 1985 | Advances in the chemistry of 2, 3-epoxyalcohols. New methodology for contra-trans-diaxial opening and selective enediol oxidation | The Journal of Organic Chemistry | article | 65 |
| 1980 | A new oxidation of aldehydes to carboxylic acids | Tetrahedron Letters | article | 65 |
| 2000 | Reaction of COTC with glutathione: structure of the putative glyoxalase I inhibitor | Organic Letters | article | 64 |
| 2011 | Trifluoroacetic anhydride-catalyzed oxidation of isonitriles by DMSO: A rapid, convenient synthesis of isocyanates | Organic Letters | article | 63 |
| 2000 | Probing the Catalytic Mechanism of Prephenate Dehydratase by Site-Directed Mutagenesis of the Escherichia coli P-Protein Dehydratase Domain | Biochemistry | article | 62 |
| 2002 | An efficient synthesis of substituted prolines by the selective reduction and reductive cyanation of 2-pyrrolidones | Tetrahedron Letters | article | 59 |
| 1996 | Site-directed mutagenesis of monofunctional chorismate mutase engineered from the E. coli P-protein | Bioorganic & Medicinal Chemistry | article | 59 |
| 1985 | Total synthesis of (.+-.)-4-amino-4-deoxychorismic acid: a key intermediate in the biosynthesis of p-aminobenzoic acid and Lp-aminophenylalanine | Journal of the American Chemical Society | article | 58 |
| 1981 | A general, highly stereoselective synthesis of amines | Tetrahedron Letters | article | 58 |
| 1978 | A new approach to substituted arene oxides. Total synthesis of senepoxide and seneol | Journal of the American Chemical Society | article | 57 |
| 2004 | Three-component condensation leading to β-amino acid diamides: convergent assembly of β-peptide analogues | Journal of the American Chemical Society | article | 54 |
| 1998 | Enantioselective approaches to aminocyclopentitols: A total synthesis of (+)-6-epitrehazolin and a formal total synthesis of (+)-trehazolin | The Journal of Organic Chemistry | article | 53 |
| 1993 | Detecting noncovalent complexes of biological macromolecules: new applications of ion-spray mass spectrometry | — | article | 52 |
| 1982 | Virginiamycin M: absolute configuration and synthetic studes | Tetrahedron Letters | article | 52 |
| 2003 | A general synthesis of 2-substituted-5-aminooxazoles: building blocks for multifunctional heterocycles | Tetrahedron Letters | article | 51 |
| 2000 | A new synthesis of the glyoxalase-I inhibitor COTC | Tetrahedron Letters | article | 51 |
| 1981 | Total synthesis of kukoamine A, an antihypertensive constituent of lycium chinense | Tetrahedron Letters | article | 51 |